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本文引用的文献

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Impact of illness and death: comparison of Load and QALY models.疾病与死亡的影响:负荷模型与质量调整生命年模型的比较
BMJ Open Qual. 2025 Mar 18;14(1):e003190. doi: 10.1136/bmjoq-2024-003190.
2
Patient-reported outcome measures (PROMs): A review of generic and condition-specific measures and a discussion of trends and issues.患者报告结局测量(PROMs):通用和特定疾病测量工具的综述,以及对趋势和问题的讨论。
Health Expect. 2021 Aug;24(4):1015-1024. doi: 10.1111/hex.13254. Epub 2021 May 5.
3
An International Comparison of EQ-5D-5L and EQ-5D-3L for Use in Cost-Effectiveness Analysis.在成本效益分析中使用 EQ-5D-5L 和 EQ-5D-3L 的国际比较。
Value Health. 2021 Apr;24(4):568-574. doi: 10.1016/j.jval.2020.11.012. Epub 2021 Jan 6.
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Assessing responsiveness of the EQ-5D-3L, the Oxford Hip Score, and the Oxford Knee Score in the NHS patient-reported outcome measures.评估 NHS 患者报告结局测量中的 EQ-5D-3L、牛津髋关节评分和牛津膝关节评分的反应度。
J Orthop Surg Res. 2021 Jan 7;16(1):18. doi: 10.1186/s13018-020-02126-2.
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Valuing health-related quality of life: An EQ-5D-5L value set for England.重视与健康相关的生活质量:英国的EQ-5D-5L价值集。
Health Econ. 2018 Jan;27(1):7-22. doi: 10.1002/hec.3564. Epub 2017 Aug 22.
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Performance of EQ-5D, howRu and Oxford hip & knee scores in assessing the outcome of hip and knee replacements.EQ-5D、howRu以及牛津髋关节与膝关节评分在评估髋关节和膝关节置换手术结果中的表现。
BMC Health Serv Res. 2016 Sep 22;16(1):512. doi: 10.1186/s12913-016-1759-x.
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Development and preliminary testing of the new five-level version of EQ-5D (EQ-5D-5L).新的 EQ-5D 五维版本(EQ-5D-5L)的制定和初步测试。
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The applications of PROs in clinical practice: what are they, do they work, and why?患者报告结局(PROs)在临床实践中的应用:它们是什么、是否有效以及原因何在?
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Interpretation of changes in health-related quality of life: the remarkable universality of half a standard deviation.健康相关生活质量变化的解读:半个标准差的显著普遍性。
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为什么EQ-5D量表与牛津髋关节和膝关节评分所衡量的内容不同。

Why EQ-5D and the Oxford Hip and Knee scores do not measure the same things.

作者信息

Benson Tim

机构信息

R-Outcomes Ltd, Newbury, UK

Institute of Health Informatics, UCL, London, UK.

出版信息

BMJ Open Qual. 2025 Jun 8;14(2):e003214. doi: 10.1136/bmjoq-2024-003214.

DOI:10.1136/bmjoq-2024-003214
PMID:40484417
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12161340/
Abstract

INTRODUCTION

The outcome of treatment is always paramount for patients and healthcare professionals. Patient-reported outcome measures have been developed to measure outcomes.Since 2009, all patients in England having hip and knee replacement surgery have been asked to complete the generic EuroQol EQ-5D-3L and EQ visual analogue scale (EQ-VAS) and the condition-specific Oxford Hip Score or Oxford Knee Score for hips and knees, respectively.

METHODS

EQ-5D-3L has five dimensions with three options each. Each combination has been scaled relative to the best conceivable health state (value 1.0) and the state of dead (value 0) to produce a relative severity score (EQ-Index) with a range from -0.594 to 1.0. This can be used to calculate quality-adjusted life-years. The EQ-VAS is a visual analogue scale from 0 (dead) to 100 (best conceivable health state).The Oxford Hip and Knee scores are similar to each other. They have 12 questions with five options each, scored 0-4. These scores are added, giving a scale with range 0 (no problems) to 48 (extreme problems on all questions).Using over 40 000 records for patients undergoing hip and knee replacements from the National Health Service patient-reported outcome measure database, we compare EQ-5D-3L with the Oxford Hip and Knee scores. To aid comparison, each score was transformed arithmetically to a common 0 (floor) to 100 (ceiling) scale.

RESULTS

EQ-Index, EQ-VAS and the Oxford scores give very different results in terms of change, effect size and correlation.

DISCUSSION

More research is needed, but some speculative ideas are put forward, which could explain these findings.

摘要

引言

治疗结果对患者和医疗保健专业人员而言始终至关重要。已开发出患者报告结局测量方法来衡量治疗结果。自2009年以来,英格兰所有接受髋关节和膝关节置换手术的患者都被要求分别完成通用的欧洲五维度健康量表EQ-5D-3L和EQ视觉模拟量表(EQ-VAS),以及针对髋关节和膝关节的特定疾病牛津髋关节评分或牛津膝关节评分。

方法

EQ-5D-3L有五个维度,每个维度有三个选项。每种组合都相对于最佳可想象健康状态(值为1.0)和死亡状态(值为0)进行了评分,以产生范围从-0.594至1.0的相对严重程度评分(EQ指数)。这可用于计算质量调整生命年。EQ-VAS是一个从0(死亡)到100(最佳可想象健康状态)的视觉模拟量表。牛津髋关节和膝关节评分彼此相似。它们有12个问题,每个问题有五个选项,评分从0到4。将这些分数相加,得出一个范围从0(无问题)到48(所有问题都有极端问题)的量表。利用来自国民保健服务患者报告结局测量数据库的40000多条髋关节和膝关节置换患者记录,我们将EQ-5D-3L与牛津髋关节和膝关节评分进行了比较。为便于比较,每个评分都通过算术转换为一个通用的从0(最低)到100(最高)的量表。

结果

EQ指数、EQ-VAS和牛津评分在变化、效应大小和相关性方面给出了非常不同的结果。

讨论

需要更多研究,但提出了一些推测性想法,这些想法可以解释这些发现。