Benson Tim
R-Outcomes Ltd, Newbury, UK
Institute of Health Informatics, UCL, London, UK.
BMJ Open Qual. 2025 Jun 8;14(2):e003214. doi: 10.1136/bmjoq-2024-003214.
The outcome of treatment is always paramount for patients and healthcare professionals. Patient-reported outcome measures have been developed to measure outcomes.Since 2009, all patients in England having hip and knee replacement surgery have been asked to complete the generic EuroQol EQ-5D-3L and EQ visual analogue scale (EQ-VAS) and the condition-specific Oxford Hip Score or Oxford Knee Score for hips and knees, respectively.
EQ-5D-3L has five dimensions with three options each. Each combination has been scaled relative to the best conceivable health state (value 1.0) and the state of dead (value 0) to produce a relative severity score (EQ-Index) with a range from -0.594 to 1.0. This can be used to calculate quality-adjusted life-years. The EQ-VAS is a visual analogue scale from 0 (dead) to 100 (best conceivable health state).The Oxford Hip and Knee scores are similar to each other. They have 12 questions with five options each, scored 0-4. These scores are added, giving a scale with range 0 (no problems) to 48 (extreme problems on all questions).Using over 40 000 records for patients undergoing hip and knee replacements from the National Health Service patient-reported outcome measure database, we compare EQ-5D-3L with the Oxford Hip and Knee scores. To aid comparison, each score was transformed arithmetically to a common 0 (floor) to 100 (ceiling) scale.
EQ-Index, EQ-VAS and the Oxford scores give very different results in terms of change, effect size and correlation.
More research is needed, but some speculative ideas are put forward, which could explain these findings.
治疗结果对患者和医疗保健专业人员而言始终至关重要。已开发出患者报告结局测量方法来衡量治疗结果。自2009年以来,英格兰所有接受髋关节和膝关节置换手术的患者都被要求分别完成通用的欧洲五维度健康量表EQ-5D-3L和EQ视觉模拟量表(EQ-VAS),以及针对髋关节和膝关节的特定疾病牛津髋关节评分或牛津膝关节评分。
EQ-5D-3L有五个维度,每个维度有三个选项。每种组合都相对于最佳可想象健康状态(值为1.0)和死亡状态(值为0)进行了评分,以产生范围从-0.594至1.0的相对严重程度评分(EQ指数)。这可用于计算质量调整生命年。EQ-VAS是一个从0(死亡)到100(最佳可想象健康状态)的视觉模拟量表。牛津髋关节和膝关节评分彼此相似。它们有12个问题,每个问题有五个选项,评分从0到4。将这些分数相加,得出一个范围从0(无问题)到48(所有问题都有极端问题)的量表。利用来自国民保健服务患者报告结局测量数据库的40000多条髋关节和膝关节置换患者记录,我们将EQ-5D-3L与牛津髋关节和膝关节评分进行了比较。为便于比较,每个评分都通过算术转换为一个通用的从0(最低)到100(最高)的量表。
EQ指数、EQ-VAS和牛津评分在变化、效应大小和相关性方面给出了非常不同的结果。
需要更多研究,但提出了一些推测性想法,这些想法可以解释这些发现。