Zinreich S J, Wang H, Updike M L, Kumar A J, Ahn H S, North R B, Rosenbaum A E
Radiology. 1985 Nov;157(2):387-90. doi: 10.1148/radiology.157.2.4048445.
The diagnostic usefulness, limitations, and adverse reactions associated with computed tomographic myelography using metrizamide were assessed for broad outpatient application. The initial approach was to examine inpatients (n = 38) with low-dose metrizamide (100 mgI/ml). This low dose was believed less likely to be associated with side effects. They were then treated as if they were outpatients, with the liberties this entailed. The consequences of needle puncture were minimized by using a 25-gauge disposable needle. Thirty-four (89%) patients remained free of side effects after the procedure. Subsequently, this technique was extended to 42 outpatients, 38 (90.5%) of whom remained asymptomatic. For comparison, 170 mgI/ml was used in another 25 outpatients, who evidenced more symptoms. The potential medical, economic, and therapeutic benefits of obviating hospitalization by safer outpatient CT myelography seem clear.
对使用甲泛葡胺的计算机体层脊髓造影在广泛门诊应用中的诊断效用、局限性及不良反应进行了评估。最初的方法是对38名住院患者使用低剂量甲泛葡胺（100 mgI/ml）进行检查。认为这种低剂量与副作用的关联较小。然后将他们当作门诊患者来对待，并给予相应的自由。使用25号一次性针头将穿刺的后果降至最低。34名（89%）患者在该操作后未出现副作用。随后，该技术扩展至42名门诊患者，其中38名（90.5%）无症状。作为对照，另外25名门诊患者使用了170 mgI/ml的剂量，他们出现了更多症状。通过更安全的门诊计算机体层脊髓造影避免住院所带来的潜在医学、经济和治疗益处似乎很明显。
