Loflin T G, Simeone J F, Mueller P R, Saini S, Stark D D, Butch R J, Brady T J, Ferrucci J T
Radiology. 1985 Nov;157(2):457-9. doi: 10.1148/radiology.157.2.4048455.
Fifty-three samples of gallbladder bile were obtained at the time of cholecystectomy from patients with the clinical diagnosis of acute or chronic cholecystitis. Five bile samples from patients with clinically normal gallbladders also were obtained. Proton magnetic resonance (MR) relaxation times, protein content, and water content were determined for the bile samples, and the data were grouped according to pathologic diagnosis, which disclosed 11 cases of acute cholecystitis, 41 cases of chronic cholecystitis, and six normal gallbladders. There was no significant difference in the mean T1 and T2 values between the groups with acute and chronic cholecystitis. Patients with chronic cholecystitis were found to have more concentrated bile than those with acute cholecystitis. Protein content varied widely within both groups of patients. We conclude that T1 and T2 relaxation times do not reliably differentiate acute from chronic cholecystitis.
在胆囊切除术时，从临床诊断为急性或慢性胆囊炎的患者中获取了53份胆囊胆汁样本。还从胆囊临床正常的患者中获取了5份胆汁样本。测定了胆汁样本的质子磁共振（MR）弛豫时间、蛋白质含量和水分含量，并根据病理诊断对数据进行分组，结果显示有11例急性胆囊炎、41例慢性胆囊炎和6个正常胆囊。急性胆囊炎组和慢性胆囊炎组之间的平均T1和T2值无显著差异。发现慢性胆囊炎患者的胆汁比急性胆囊炎患者的胆汁更浓缩。两组患者的蛋白质含量差异很大。我们得出结论，T1和T2弛豫时间不能可靠地区分急性胆囊炎和慢性胆囊炎。
