McCarthy S, Hricak H, Cohen M, Fisher M R, Winkler M L, Filly R A, Margulis A R
Radiology. 1986 Feb;158(2):333-6. doi: 10.1148/radiology.158.2.3510441.
The role of magnetic resonance (MR) imaging in the detection of gallbladder disease was evaluated in 39 individuals (16 healthy, five with asymptomatic gallstones, and 18 with clinical symptoms of gallbladder disease). MR imaging was performed after they fasted for 12 hours. Imaging sequences included a combination of repetition times (TR) of 0.5 and 1.5 sec and echo times (TE) of 28 and 56 msec. On the images obtained at TR = 0.5 sec and TE = 56 msec, gallbladder bile was hyperintense compared with the liver in all healthy and asymptomatic subjects and was hypointense (n = 9), isointense (n = 4), or hyperintense (n = 5) in symptomatic patients, eight of whom had surgical confirmation of cholecystitis. Comparison of normal versus pathologically proved cases for the presence of gallbladder disease yielded a specificity of 100%, sensitivity of 75%, and a significant difference of P less than .01. Thus, with a pulse sequence of TR = 0.5 sec and TE = 56 msec, MR was sensitive in detecting gallbladder disease. However, the role of MR in the radiologic workup of gallbladder disease will be determined by more experience with this modality.
对39例个体（16例健康者、5例无症状胆结石患者以及18例有胆囊疾病临床症状者）评估了磁共振（MR）成像在胆囊疾病检测中的作用。在他们禁食12小时后进行MR成像。成像序列包括重复时间（TR）为0.5秒和1.5秒以及回波时间（TE）为28毫秒和56毫秒的组合。在TR = 0.5秒和TE = 56毫秒获得的图像上，在所有健康和无症状受试者中，胆囊胆汁相对于肝脏呈高信号，而在有症状患者中呈低信号（n = 9）、等信号（n = 4）或高信号（n = 5），其中8例经手术证实为胆囊炎。比较正常与经病理证实的胆囊疾病病例，特异性为100%，敏感性为75%，且P值小于0.01，差异有统计学意义。因此，采用TR = 0.5秒和TE = 56毫秒的脉冲序列时，MR对检测胆囊疾病很敏感。然而，MR在胆囊疾病影像学检查中的作用将取决于对这种检查方式的更多经验。
