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瑞士合成代谢雄性类固醇药物检测服务实施情况评估:一项试点研究。

Evaluation of implementing drug checking services for anabolic androgenic steroids in Switzerland: a pilot study.

作者信息

Magnolini Raphael, Kaeppeli Michel, Schori Dominique, Bruggmann Philip, Senn Oliver

机构信息

Arud Centre for Addiction Medicine, Schuetzengasse 31, 8001, Zurich, Switzerland.

Institute of Primary Care, University of Zurich and University Hospital Zurich, Zurich, Switzerland.

出版信息

Harm Reduct J. 2025 Jun 8;22(1):100. doi: 10.1186/s12954-025-01242-8.

Abstract

BACKGROUND

The use of anabolic androgenic steroids (AAS) among male recreational gym users has become a global substance use concern. A substantial black market for these substances exists with possibly extensive counterfeiting. Drug checking services (DCS) are established harm reduction services for people who consume illicit substances. To evaluate the feasibility of implementing a novel specialized DCS for AAS, a pilot study was conducted within a pre-existing DCS in Zurich (Switzerland).

METHODS

The reporting of this pilot study follows an adapted CONSORT statement. Further aims were to characterize AAS use as well as the chemical properties of customer-provided substance samples analysed through the DCS in a Swiss context. Customers could access DCS in Zurich from August 2023 onwards by providing a voluntary user questionnaire and dispense samples of AAS. Primary feasibility outcomes for this study were customer satisfaction metrics with the DCS received (i.e., customer satisfaction score (CSAT); net promoter score (NPS)). The chemical analytical method utilized was gas chromatography-mass spectrometry (GC-MS). Descriptive statistics were used.

RESULTS

Overall, 52 clients accessed DCS over the pilot period and 71 samples were chemically assessed. Excellent results regarding customer satisfaction metrics towards DCS for AAS were achieved (NPS: 97 (integer); CSAT: 93%). The typical clients were males partaking in recreational sports, between 22 and 40 years old, working, and with a higher education. The main motivation for using AAS was for aesthetic purposes. Patterns of AAS use were complex with frequent extensive concomitant substances use. Most AAS in this sample were acquired from non-medical sources. The sample analysis revealed that over half (52%) of the user-provided samples of AAS were fake.

CONCLUSIONS

We demonstrate that the implementation of DCS for AAS was feasible with high acceptance among clients. Those clients may engage in many high-risk behaviors and the use of substances with low chemical properties may expose them to additional unexpected health risks. As a harm reduction tool, DCS for these clients and substances appears to be feasible and it may further serve as monitoring tool for public health purposes. Upon the initial study results, DCS for AAS were continued with close monitoring.

摘要

背景

在男性健身爱好者中使用合成代谢雄激素类固醇(AAS)已成为全球关注的物质使用问题。这些物质存在大量黑市,可能存在广泛的假冒现象。药物检测服务(DCS)是为消费非法物质的人设立的减少伤害服务。为了评估实施针对AAS的新型专门DCS的可行性,在瑞士苏黎世现有的DCS内进行了一项试点研究。

方法

本试点研究的报告遵循改编后的CONSORT声明。进一步的目标是在瑞士背景下,描述AAS的使用情况以及通过DCS分析的客户提供的物质样本的化学性质。从2023年8月起,客户可以通过提供自愿用户问卷并提供AAS样本,使用苏黎世的DCS。本研究的主要可行性结果是客户对所接受的DCS的满意度指标(即客户满意度得分(CSAT);净促进者得分(NPS))。所采用的化学分析方法是气相色谱 - 质谱联用(GC - MS)。使用描述性统计。

结果

总体而言,在试点期间有52名客户使用了DCS,对71个样本进行了化学评估。在针对AAS的DCS客户满意度指标方面取得了优异结果(NPS:97(整数);CSAT:93%)。典型客户是年龄在22至40岁之间、有工作且受过高等教育的男性,参与休闲运动。使用AAS的主要动机是出于审美目的。AAS的使用模式复杂,经常大量同时使用其他物质。该样本中的大多数AAS是从非医疗渠道获得的。样本分析显示,超过一半(52%)的用户提供的AAS样本是假冒的。

结论

我们证明,实施针对AAS的DCS是可行的,客户接受度很高。这些客户可能会从事许多高风险行为,使用化学性质不明的物质可能会使他们面临额外的意外健康风险。作为一种减少伤害的工具,针对这些客户和物质的DCS似乎是可行的,并且它还可以作为公共卫生目的的监测工具。根据初步研究结果,继续对AAS的DCS进行密切监测。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ce97/12147309/aad9791e4f65/12954_2025_1242_Fig1_HTML.jpg

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