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Lymphocyte Transformation Test: A Promising Tool for Identifying the Causative Agent in Drug-Induced Acute Interstitial Nephritis.

作者信息

Moreno Javier Azores, Cabañas Rosario, Bellón Teresa, Fernández Eugenia García, Raso Irene Vázquez, Aldana Sara, Maldonado María, León-Machado Lina, Shabaka Amir, Becerra Begoña Rivas, Cabrera Cristina Vega, Juárez Gema Fernández

机构信息

Department of Nephrology, Hospital Universitario La Paz, Madrid, Spain.

Department of Allergy, Hospital Universitario La Paz, Madrid, Spain.

出版信息

Kidney Int Rep. 2025 Mar 6;10(5):1562-1565. doi: 10.1016/j.ekir.2025.02.029. eCollection 2025 May.

DOI:10.1016/j.ekir.2025.02.029
PMID:40485678
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12142607/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8785/12142607/7704995017bd/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8785/12142607/7704995017bd/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8785/12142607/7704995017bd/gr1.jpg

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Lymphocyte Transformation Test: A Promising Tool for Identifying the Causative Agent in Drug-Induced Acute Interstitial Nephritis.淋巴细胞转化试验:一种用于识别药物性急性间质性肾炎致病因子的有前景的工具。
Kidney Int Rep. 2025 Mar 6;10(5):1562-1565. doi: 10.1016/j.ekir.2025.02.029. eCollection 2025 May.
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本文引用的文献

1
Diagnosis and management of immune checkpoint inhibitor-associated acute kidney injury.免疫检查点抑制剂相关急性肾损伤的诊断与管理
Nat Rev Nephrol. 2022 Dec;18(12):794-805. doi: 10.1038/s41581-022-00630-8. Epub 2022 Sep 27.
2
Recurrent acute interstitial nephritis: what lies beneath.复发性急性间质性肾炎:病因何在。
Clin Kidney J. 2020 Mar 11;14(1):197-204. doi: 10.1093/ckj/sfaa018. eCollection 2021 Jan.
3
Immune Checkpoint Inhibitors and Immune-Related Adverse Renal Events.免疫检查点抑制剂与免疫相关的肾脏不良事件
Kidney Int Rep. 2020 Apr 29;5(8):1139-1148. doi: 10.1016/j.ekir.2020.04.018. eCollection 2020 Aug.
4
The Incidence, Causes, and Risk Factors of Acute Kidney Injury in Patients Receiving Immune Checkpoint Inhibitors.免疫检查点抑制剂治疗患者急性肾损伤的发生率、病因和危险因素。
Clin J Am Soc Nephrol. 2019 Dec 6;14(12):1692-1700. doi: 10.2215/CJN.00990119. Epub 2019 Oct 31.
5
Assessment of drug causality in Stevens-Johnson syndrome/toxic epidermal necrolysis: Concordance between lymphocyte transformation test and ALDEN.史蒂文斯-约翰逊综合征/中毒性表皮坏死松解症中药物因果关系的评估:淋巴细胞转化试验与ALDEN之间的一致性
Allergy. 2020 Apr;75(4):956-959. doi: 10.1111/all.14062. Epub 2019 Oct 21.
6
Duration of Treatment with Corticosteroids and Recovery of Kidney Function in Acute Interstitial Nephritis.皮质类固醇治疗时间与急性间质性肾炎的肾功能恢复。
Clin J Am Soc Nephrol. 2018 Dec 7;13(12):1851-1858. doi: 10.2215/CJN.01390118. Epub 2018 Nov 5.
7
Sensitivity and specificity of the lymphocyte transformation test in drug reaction with eosinophilia and systemic symptoms causality assessment.淋巴细胞转化试验在药物相关性嗜酸性粒细胞增多和全身症状因果关系评估中的敏感性和特异性。
Clin Exp Allergy. 2018 Mar;48(3):325-333. doi: 10.1111/cea.13076. Epub 2018 Jan 19.
8
Clinicopathological features of acute kidney injury associated with immune checkpoint inhibitors.与免疫检查点抑制剂相关的急性肾损伤的临床病理特征
Kidney Int. 2016 Sep;90(3):638-47. doi: 10.1016/j.kint.2016.04.008. Epub 2016 Jun 7.
9
The lymphocyte transformation test in the diagnosis of drug hypersensitivity.淋巴细胞转化试验在药物过敏诊断中的应用
Allergy. 2004 Aug;59(8):809-20. doi: 10.1111/j.1398-9995.2004.00547.x.