• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

为一名曾接受心肺移植的患者因侵袭性肺拟青霉病进行再次双侧肺移植。

Redo bilateral lung transplantation in a previous heart-lung transplant recipient for invasive pulmonary scedosporiosis.

作者信息

Chauhan Akshay, Ranganath Nischal, Scott John P, Vergidis Paschalis, Roden Anja C, Spencer Philip J, Villavicencio Mauricio A, Daly Richard C, Saddoughi Sahar A

机构信息

Department of Cardiovascular Surgery, Mayo Clinic, Rochester, Minnesota.

Section of Infectious Disease, Department of Medicine, Mayo Clinic, Rochester, Minnesota.

出版信息

JHLT Open. 2025 Apr 1;8:100247. doi: 10.1016/j.jhlto.2025.100247. eCollection 2025 May.

DOI:10.1016/j.jhlto.2025.100247
PMID:40486111
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12142616/
Abstract

Redo-bilateral lung transplant in previous heart-lung transplant is a rare operation. We describe our surgical and medical management experience with a heart-lung transplant recipient who developed chronic lung allograft dysfunction and invasive apiospermum infection. The patient underwent a redo-bilateral lung transplant followed by a combination of inhaled voriconazole, caspofungin, and olorofim for a prolonged period. We observed no issues with bronchial anastomosis healing, and the patient is doing well on 1-year follow-up. This report outlines a successful management approach to this rare complication of heart-lung transplant recipients.

摘要

既往心肺移植患者再次进行双侧肺移植是一种罕见的手术。我们描述了一名心肺移植受者出现慢性肺移植功能障碍和侵袭性阿皮芽孢菌感染后的手术及内科治疗经验。该患者接受了再次双侧肺移植，随后长期联合使用吸入伏立康唑、卡泊芬净和奥拉氟进行治疗。我们观察到支气管吻合口愈合无问题，患者在1年随访时情况良好。本报告概述了针对心肺移植受者这种罕见并发症的成功管理方法。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2381/12142616/e086e97badb0/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2381/12142616/8a419e5274b9/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2381/12142616/2fc2f98f498e/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2381/12142616/e086e97badb0/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2381/12142616/8a419e5274b9/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2381/12142616/2fc2f98f498e/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2381/12142616/e086e97badb0/gr3.jpg

相似文献

1
Redo bilateral lung transplantation in a previous heart-lung transplant recipient for invasive pulmonary scedosporiosis.为一名曾接受心肺移植的患者因侵袭性肺拟青霉病进行再次双侧肺移植。
JHLT Open. 2025 Apr 1;8:100247. doi: 10.1016/j.jhlto.2025.100247. eCollection 2025 May.
2
Epidemiology, clinical manifestations, and outcomes of Scedosporium infections among solid organ transplant recipients.实体器官移植受者中赛多孢菌感染的流行病学、临床表现及转归
Transpl Infect Dis. 2014 Aug;16(4):578-87. doi: 10.1111/tid.12244. Epub 2014 Jun 24.
3
mediastinitis in an orthotopic heart transplant recipient.原位心脏移植受者的纵隔炎
IJID Reg. 2022 Sep 28;5:117-120. doi: 10.1016/j.ijregi.2022.09.011. eCollection 2022 Dec.
4
[Scedosporium apiospermum disseminated infection in a single lung transplant recipient].[1例肺移植受者播散性阿皮瘤状瓶霉感染]
Rev Iberoam Micol. 2011 Jul-Sep;28(3):139-42. doi: 10.1016/j.riam.2011.06.007.
5
Invasive scedosporiosis in lung transplant recipients: A nine-year retrospective study in a tertiary care hospital.肺移植受者侵袭性粗球孢子菌病：一家三级医院的 9 年回顾性研究。
Rev Iberoam Micol. 2021 Oct-Dec;38(4):184-187. doi: 10.1016/j.riam.2021.06.002. Epub 2021 Oct 10.
6
Effective Prolonged Therapy with Voriconazole in a Lung Transplant Recipient with Spondylodiscitis Induced by Scedosporium apiospermum.伏立康唑对一名由尖端赛多孢菌引起的脊椎盘炎的肺移植受者进行有效长期治疗。
Case Rep Infect Dis. 2011;2011:460313. doi: 10.1155/2011/460313. Epub 2011 Aug 1.
7
Pneumonia With Scedosporium apiospermum and Lomentospora prolificans in a Patient After Bilateral Lung Transplantation for Pulmonary Hypertension: A Case Report.一名因肺动脉高压接受双侧肺移植的患者发生了由阿氏瓶霉和多育镰孢菌引起的肺炎：病例报告
Transplant Proc. 2021 May;53(4):1375-1378. doi: 10.1016/j.transproceed.2021.02.002. Epub 2021 Mar 8.
8
Efficacy of Olorofim against Systemic Scedosporiosis and Lomentosporiosis.奥洛罗芬治疗系统性足分枝菌病和罗麦孢菌病的疗效
Antimicrob Agents Chemother. 2021 Sep 17;65(10):e0043421. doi: 10.1128/AAC.00434-21. Epub 2021 Jul 12.
9
Pulmonary scedosporiosis mimicking aspergilloma in an immunocompetent host: a case report and review of the literature.免疫功能正常宿主中表现为曲菌球的肺拟青霉病：一例报告并文献复习
Infection. 2016 Feb;44(1):127-32. doi: 10.1007/s15010-015-0840-4. Epub 2015 Sep 9.
10
The effect of allograft ischemic time on outcomes following bilateral, single, and reoperative lung transplantation.同种异体移植物缺血时间对双侧、单肺和再次肺移植术后结果的影响。
J Thorac Cardiovasc Surg. 2024 Feb;167(2):556-565.e8. doi: 10.1016/j.jtcvs.2023.05.027. Epub 2023 Jun 5.

本文引用的文献

1
Sequential redo-bilateral lung transplantation in recipient with prior heart-lung transplantation with tracheal anastomosis.先前接受心肺移植并进行气管吻合术的受者进行序贯再次双侧肺移植。
JTCVS Tech. 2023 Apr 8;19:160-163. doi: 10.1016/j.xjtc.2023.03.017. eCollection 2023 Jun.
2
Efficacy of Olorofim against Systemic Scedosporiosis and Lomentosporiosis.奥洛罗芬治疗系统性足分枝菌病和罗麦孢菌病的疗效
Antimicrob Agents Chemother. 2021 Sep 17;65(10):e0043421. doi: 10.1128/AAC.00434-21. Epub 2021 Jul 12.
3
Perspectives on Scedosporium species and Lomentospora prolificans in lung transplantation: Results of an international practice survey from ESCMID fungal infection study group and study group for infections in compromised hosts, and European Confederation of Medical Mycology.
肺移植中赛多孢菌属和多育镰刀菌的研究现状：欧洲临床微生物与感染性疾病学会真菌感染研究组、免疫功能低下宿主感染研究组及欧洲医学真菌联合会的一项国际实践调查结果
Transpl Infect Dis. 2019 Oct;21(5):e13141. doi: 10.1111/tid.13141. Epub 2019 Jul 22.
4
Species-specific antifungal susceptibility patterns of Scedosporium and Pseudallescheria species.棘孢木霉属和拟青霉属种的种特异性抗真菌药敏模式。
Antimicrob Agents Chemother. 2012 May;56(5):2635-42. doi: 10.1128/AAC.05910-11. Epub 2012 Jan 30.
5
Revision of the 1996 working formulation for the standardization of nomenclature in the diagnosis of lung rejection.1996年肺移植排斥反应诊断命名标准化工作方案的修订版。
J Heart Lung Transplant. 2007 Dec;26(12):1229-42. doi: 10.1016/j.healun.2007.10.017.
6
Infections due to Scedosporium apiospermum and Scedosporium prolificans in transplant recipients: clinical characteristics and impact of antifungal agent therapy on outcome.移植受者中由尖端赛多孢子菌和多育赛多孢子菌引起的感染：临床特征及抗真菌药物治疗对结局的影响。
Clin Infect Dis. 2005 Jan 1;40(1):89-99. doi: 10.1086/426445. Epub 2004 Dec 8.
7
Coronary tracheal collaterals after heart-lung transplant.
Am J Cardiol. 2003 Dec 15;92(12):1490-2. doi: 10.1016/j.amjcard.2003.08.071.