一名年轻女性的乳腺佩吉特病：罕见病例。

Mammary Paget's disease in a young woman: A rare occurrence.

作者信息

Abourak Chaimae, Laridi Aya, Chahboune Ouafaa, Oukassem Siham, Guennouni Asmae, Bahha Soukaina, Belkouchi Lina, Allali Nazik, Chat Latifa, El Haddad Siham

机构信息

Department of Radiology, Mother-Child, Faculty of Medicine and Pharmacy of Rabat, Children's Hospital, Ibn Sina University Hospital, Mohammed V University, Rabat, Morocco.

出版信息

Radiol Case Rep. 2025 May 15;20(8):3733-3737. doi: 10.1016/j.radcr.2025.04.062. eCollection 2025 Aug.

DOI:10.1016/j.radcr.2025.04.062

PMID:40486154

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12144428/

Abstract

Mammary Paget's disease (MPD) is a rare intraepithelial carcinoma involving the nipple-areolar complex, often linked to underlying ductal carcinoma. We report a case of a 47-year-old woman presenting with progressive swelling of the left nipple, without pain, discharge, or inflammatory signs. Imaging revealed ductal dilation and nipple thickening, classified as BI-RADS 4, with MRI confirming additional suspicious findings. Histopathological analysis of a biopsy confirmed MPD associated with underlying ductal carcinoma in situ. This case underscores the importance of multimodal imaging and histopathology in diagnosing and managing this uncommon breast malignancy.

摘要

乳腺佩吉特病（MPD）是一种罕见的上皮内癌，累及乳头乳晕复合体，常与潜在的导管癌相关。我们报告一例47岁女性，表现为左乳头进行性肿胀，无疼痛、溢液或炎症体征。影像学检查显示导管扩张和乳头增厚，分类为BI-RADS 4级，MRI证实有其他可疑发现。活检的组织病理学分析证实为MPD伴潜在原位导管癌。该病例强调了多模态成像和组织病理学在诊断和管理这种罕见乳腺恶性肿瘤中的重要性。