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运用不同组学策略表征鹿茸的治疗效果。

Characterizing therapeutic effects of velvet antler using different omics strategies.

作者信息

Ho Shang-Tse, Kuo Ching-Yun, Chen Ming-Ju

机构信息

Department of Wood Based Materials and Design, National Chiayi University, Chiayi, 600, Taiwan.

Taiwan Livestock Research Institute, Council of Agriculture, Tainan, 712, Taiwan.

出版信息

J Tradit Complement Med. 2024 Aug 13;15(3):229-236. doi: 10.1016/j.jtcme.2024.08.002. eCollection 2025 May.

Abstract

Velvet antler (VA) has been widely used in traditional Chinese medicine more than thousand years. Several pharmacological properties of VA have been demonstrated, such as anti-osteoporosis, anti-osteoarthritis, anti-aging, and anti-ischemia-hypoxia effects. Recently, many studies applied different omics in VA studies to illustrate biological pathways or processes, identify bioactive compounds, and discover pharmacological properties. This mini-review article summarizes the application of different omics for investigating therapeutic effects of VA. The limitation and future challenges facing the application of multi-omics in VA is also briefly discussed.

摘要

鹿茸(VA)在传统中医中已被广泛应用了一千多年。鹿茸的多种药理特性已得到证实,如抗骨质疏松、抗骨关节炎、抗衰老以及抗缺血缺氧作用。最近,许多研究将不同的组学技术应用于鹿茸研究,以阐明生物学途径或过程、鉴定生物活性化合物并发现药理特性。这篇综述性短文总结了不同组学在研究鹿茸治疗作用方面的应用。同时也简要讨论了多组学在鹿茸应用中面临的局限性和未来挑战。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d1f5/12143323/5699c770bcba/ga1.jpg

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