• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

近期接种疫苗后发生自身免疫性溶血性贫血及疑似急性出血性播散性脑脊髓炎的罕见病例

A Rare Case of Autoimmune Hemolytic Anemia and Suspected Acute Hemorrhagic Disseminated Encephalomyelitis Following Recent Vaccination.

作者信息

Karunaratne Hettiyadura Apsara Surangani Mendis, De Silva Karunakalage Anya A

机构信息

Department of General Medicine, North West Regional Hospital, Burnie, AUS.

出版信息

Cureus. 2025 May 6;17(5):e83556. doi: 10.7759/cureus.83556. eCollection 2025 May.

DOI:10.7759/cureus.83556
PMID:40486324
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12141602/
Abstract

Autoimmune hemolytic anemia (AIHA) and acute disseminated encephalomyelitis (ADEM) are rare autoimmune complications that may follow infections or vaccinations. We present a case of a 77-year-old male patient who developed warm AIHA and rapid neurological decline suggestive of hemorrhagic ADEM following recent varicella and influenza vaccinations. Laboratory findings confirmed AIHA, and MRI revealed multifocal white matter lesions with hemorrhagic foci. Despite high-dose corticosteroid treatment, the patient's condition worsened, and he ultimately passed away.

摘要

自身免疫性溶血性贫血（AIHA）和急性播散性脑脊髓炎（ADEM）是感染或接种疫苗后可能出现的罕见自身免疫性并发症。我们报告一例77岁男性患者，在近期接种水痘和流感疫苗后出现温抗体型自身免疫性溶血性贫血以及提示出血性急性播散性脑脊髓炎的快速神经功能衰退。实验室检查结果确诊为自身免疫性溶血性贫血，磁共振成像（MRI）显示多灶性白质病变伴出血灶。尽管给予了大剂量皮质类固醇治疗，患者病情仍恶化，最终死亡。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4144/12141602/d3b6140b153c/cureus-0017-00000083556-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4144/12141602/cc7036941bae/cureus-0017-00000083556-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4144/12141602/d3b6140b153c/cureus-0017-00000083556-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4144/12141602/cc7036941bae/cureus-0017-00000083556-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4144/12141602/d3b6140b153c/cureus-0017-00000083556-i02.jpg

相似文献

1
A Rare Case of Autoimmune Hemolytic Anemia and Suspected Acute Hemorrhagic Disseminated Encephalomyelitis Following Recent Vaccination.近期接种疫苗后发生自身免疫性溶血性贫血及疑似急性出血性播散性脑脊髓炎的罕见病例
Cureus. 2025 May 6;17(5):e83556. doi: 10.7759/cureus.83556. eCollection 2025 May.
2
Pediatric Acute Disseminated Encephalomyelitis Triggered by Concurrent Administration of Seasonal and H1N1 Influenza Vaccines: A Case Report and Review.季节性流感疫苗与甲型H1N1流感疫苗同时接种引发的小儿急性播散性脑脊髓炎：一例报告及文献复习
NeuroSci. 2024 Dec 30;6(1):1. doi: 10.3390/neurosci6010001.
3
Acute disseminated encephalomyelitis with severe neurological outcomes following virosomal seasonal influenza vaccine.使用病毒体季节性流感疫苗后出现严重神经学后果的急性播散性脑脊髓炎
Hum Vaccin Immunother. 2014;10(7):1969-73. doi: 10.4161/hv.28961.
4
Acute haemorrhagic leukoencephalitis (AHLE) - our experience and a short review.急性出血性白质脑炎（AHLE）——我们的经验与简短综述。
J Neuroimmunol. 2021 Dec 15;361:577751. doi: 10.1016/j.jneuroim.2021.577751. Epub 2021 Oct 13.
5
An interesting case of acute disseminated encephalomyelitis following infection.一例感染后急性播散性脑脊髓炎的有趣病例。
J Family Med Prim Care. 2019 Jan;8(1):292-295. doi: 10.4103/jfmpc.jfmpc_402_18.
6
A Rare Case of Warm Autoimmune Hemolytic Anemia With Intravascular Hemolysis: A Case Report.1例伴有血管内溶血的温抗体型自身免疫性溶血性贫血罕见病例：病例报告
Cureus. 2025 May 11;17(5):e83916. doi: 10.7759/cureus.83916. eCollection 2025 May.
7
Acute Disseminated Encephalomyelitis and Acute Encephalitis Following Vaccination Against SARS-CoV-2: Two Case Reports and Review of Literature.接种 SARS-CoV-2 疫苗后出现急性播散性脑脊髓炎和急性脑炎：两例病例报告及文献复习。
Fortschr Neurol Psychiatr. 2023 Jul;91(7-08):319-325. doi: 10.1055/a-2029-4405. Epub 2023 Mar 17.
8
Neurological complications of influenza vaccination: navigating the spectrum with a focus on acute disseminated encephalomyelitis (ADEM).流感疫苗接种的神经系统并发症：聚焦急性播散性脑脊髓炎（ADEM）全面解析
Ann Med Surg (Lond). 2024 Jan 3;86(2):1029-1041. doi: 10.1097/MS9.0000000000001656. eCollection 2024 Feb.
9
Warm and Cold Autoimmune Hemolytic Anemia in the Setting of COVID-19 Disease.新冠病毒疾病背景下的温抗体型和冷抗体型自身免疫性溶血性贫血
Cureus. 2021 Sep 20;13(9):e18127. doi: 10.7759/cureus.18127. eCollection 2021 Sep.
10
Rare case of refractory mixed autoimmune hemolytic anemia in a 6-year-old child: a case report.6 岁儿童难治性混合自身免疫性溶血性贫血 1 例报告
J Med Case Rep. 2023 Oct 5;17(1):418. doi: 10.1186/s13256-023-04154-y.

本文引用的文献

1
Autoimmune haemolytic anaemia and immune thrombocytopenia following SARS-CoV-2 and non-SARS-CoV-2 vaccination: 32 Years of passive surveillance data.新型冠状病毒病和非新型冠状病毒病疫苗接种后的自身免疫性溶血性贫血和免疫性血小板减少症：32 年的被动监测数据。
Br J Haematol. 2023 Apr;201(2):227-233. doi: 10.1111/bjh.18627. Epub 2022 Dec 23.
2
Development and exacerbation of autoimmune hemolytic anemia following COVID-19 vaccination: A systematic review.接种 COVID-19 疫苗后自身免疫性溶血性贫血的发展和加重：系统评价。
Int J Lab Hematol. 2023 Apr;45(2):145-155. doi: 10.1111/ijlh.13978. Epub 2022 Oct 8.
3
Acute Demyelinating Events Following Vaccines: A Case-Centered Analysis.
疫苗接种后的急性脱髓鞘事件：以病例为中心的分析
Clin Infect Dis. 2016 Dec 1;63(11):1456-1462. doi: 10.1093/cid/ciw607. Epub 2016 Sep 1.
4
Acute disseminated encephalomyelitis in 228 patients: A retrospective, multicenter US study.228例急性播散性脑脊髓炎患者：一项美国多中心回顾性研究。
Neurology. 2016 May 31;86(22):2085-93. doi: 10.1212/WNL.0000000000002723. Epub 2016 May 4.
5
A Case of Acute Disseminated Encephalomyelitis in a Middle-Aged Adult.一例中年成人急性播散性脑脊髓炎病例
Case Rep Neurol Med. 2015;2015:601706. doi: 10.1155/2015/601706. Epub 2015 Jun 9.
6
Autoimmune hemolytic anemia following MF59-adjuvanted influenza vaccine administration: a report of two cases.接种 MF59 佐剂流感疫苗后发生自身免疫性溶血性贫血：两例报告。
Ann Pharmacother. 2011 Jan;45(1):e8. doi: 10.1345/aph.1P480. Epub 2010 Dec 28.
7
Acute disseminated encephalomyelitis: a follow-up study of 40 adult patients.急性播散性脑脊髓炎：40例成年患者的随访研究
Neurology. 2001 May 22;56(10):1313-8. doi: 10.1212/wnl.56.10.1313.