Tong Clara, Kong Aaron, Ithnin Farida, Sng Ban Leong
Department of Anaesthesiology and Surgical Intensive Care, Changi General Hospital, Singapore, SGP.
Department of Women's Anaesthesia, KK Women's and Children's Hospital, Singapore, SGP.
Cureus. 2025 May 6;17(5):e83605. doi: 10.7759/cureus.83605. eCollection 2025 May.
Pre-eclampsia (PE) and peripartum cardiomyopathy (PPCM) are two types of complications that can occur in pregnancy and the peripartum period. We present the successful management of a pre-eclamptic patient with severe, undifferentiated pulmonary oedema in pregnancy. Our patient presented at 35 + 5 weeks of gestational age with hypertension, delirium and severe hypoxaemia. She developed pulseless electrical activity after induction of general anaesthesia for a category one caesarean section. Resuscitation commenced, and a peri-mortem caesarean section was performed. Spontaneous circulation returned nine minutes after arrest. Post-operative evaluation in the intensive care unit revealed elevated natriuretic peptide levels, cardiomegaly and left ventricular ejection fraction of 20%-25%. Pulmonary oedema associated with PE and PPCM may have similar clinical features but may be distinguished with a targeted bedside echocardiogram. This guides disease-specific management and prognostication. Strategies to prevent severe hypoxaemia during laryngoscopy and intubation may also be considered. These cases require expert care and good inter-disciplinary team dynamics to ensure a favourable patient outcome.
子痫前期(PE)和围产期心肌病(PPCM)是妊娠和围产期可能发生的两种并发症。我们介绍了一名妊娠合并严重、未分化肺水肿的子痫前期患者的成功治疗案例。我们的患者在孕35 + 5周时出现高血压、谵妄和严重低氧血症。在进行一级剖宫产全身麻醉诱导后,她出现了无脉电活动。开始进行复苏,并实施了濒死剖宫产。心脏骤停九分钟后恢复了自主循环。重症监护病房的术后评估显示利钠肽水平升高、心脏扩大以及左心室射血分数为20% - 25%。与PE和PPCM相关的肺水肿可能具有相似的临床特征,但可通过有针对性的床边超声心动图进行区分。这有助于指导针对特定疾病的管理和预后评估。也可考虑在喉镜检查和插管期间预防严重低氧血症的策略。这些病例需要专家护理和良好的跨学科团队协作,以确保患者获得良好的治疗结果。