Division of Plastic and Reconstructive Surgery, McGill University Health Centre, Montreal, Canada.
McGill University, Montreal, Canada.
Aesthet Surg J. 2021 Jun 14;41(7):NP948-NP958. doi: 10.1093/asj/sjab119.
Although many interventions are implemented to prevent surgical site infections (SSIs) in plastic surgery, their supporting evidence is inconsistent.
The goal of this study was to assess the efficacy of methods for decreasing SSIs in plastic surgery.
A systematic review and meta-analysis were performed to compare the effects of SSI prevention methods. All the studies were assessed for quality of evidence according to the GRADE assessment.
Fifty Level 1 randomized controlled trials were included. The most common interventions for preventing SSIs were antibiotic prophylaxis, showering, prepping, draping, and the use of dressings. Current evidence suggests that antibiotic prophylaxis is largely unnecessary and overused in many plastic surgical procedures, with the exception of head and neck oncologic, oral craniofacial, and traumatic hand surgeries.
Efficacy of antibiotic prophylaxis in plastic surgery is dependent on surgery type. There is a lack evidence that showering and prepping with chlorohexidine and povidone reduces SSIs.
尽管有许多干预措施被用于预防整形手术中的手术部位感染（SSI），但其支持证据并不一致。
本研究旨在评估减少整形手术中 SSI 的方法的疗效。
进行了系统评价和荟萃分析，以比较 SSI 预防方法的效果。根据 GRADE 评估，对所有研究进行了证据质量评估。
共纳入 50 项 1 级随机对照试验。预防 SSI 最常用的干预措施包括抗生素预防、沐浴、备皮、铺巾和使用敷料。目前的证据表明，抗生素预防在许多整形手术中大多是不必要的和过度使用的，除了头颈部肿瘤、口腔颅面和创伤性手部手术。
抗生素预防在整形手术中的疗效取决于手术类型。缺乏证据表明氯己定和聚维酮沐浴和备皮可降低 SSI。
