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高血压患者的血镉与血浆锌水平。附76例报告

[Blood cadmium and plasma zinc in hypertensive patients. Apropos of 76 cases].

作者信息

Bartolin R, Bouvenot G, Arnaud C, Turzanski J M, Gadroy P, Rey P A

出版信息

Rev Med Interne. 1985 Jun;6(3):280-4. doi: 10.1016/s0248-8663(85)80118-1.

DOI:10.1016/s0248-8663(85)80118-1
PMID:4048689
Abstract

Changes in total blood cadmium level (CdT), in blood plasma Zinc level (ZnP) and in CdT/ZnP ratio were studied in 39 hypertensive patients compared to 37 healthy subjects. The hypertensive patients were caracterized by a higher CdT level (p less than 10(-5)), a lower ZnP level (p less than 10(-7)) and a higher CdT/ZnP ratio (p less than 10(-7)). A negative correlation was found between CdT and ZnP, and between blood pressure values (systolic and diastolic) and ZnP. A positive correlation was found between blood pressure values and CdT, and therefore CdT/ZnP ratio.

摘要

对39名高血压患者和37名健康受试者的全血镉水平(CdT)、血浆锌水平(ZnP)及CdT/ZnP比值的变化进行了研究。高血压患者的特征为CdT水平较高(p<10⁻⁵)、ZnP水平较低(p<10⁻⁷)以及CdT/ZnP比值较高(p<10⁻⁷)。发现CdT与ZnP之间、血压值(收缩压和舒张压)与ZnP之间呈负相关。还发现血压值与CdT以及CdT/ZnP比值之间呈正相关。

相似文献

1
[Blood cadmium and plasma zinc in hypertensive patients. Apropos of 76 cases].高血压患者的血镉与血浆锌水平。附76例报告
Rev Med Interne. 1985 Jun;6(3):280-4. doi: 10.1016/s0248-8663(85)80118-1.
2
Plasma cadmium and zinc in human hypertension.人类高血压患者血浆中的镉和锌
Clin Sci Mol Med. 1976 Nov;51(5):483-6. doi: 10.1042/cs0510483.
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Sem Hop. 1980;56(41-42):1718-9.
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Zinc, cadmium, and hypertension in parturient women.产妇中的锌、镉与高血压
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Role of elements in pathophysiology of hypertension and antihypertensive drug development.元素在高血压病理生理学及抗高血压药物研发中的作用
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Blood cadmium and plasma zinc measurements in acute myocardial infarction.急性心肌梗死患者血液镉和血浆锌的测定
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Clin Chim Acta. 1982 Jul 1;122(2):189-202. doi: 10.1016/0009-8981(82)90278-9.
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Blood-cadmium levels in normotensive and untreated hypertensive humans.
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Sci Total Environ. 2008 Dec 15;407(1):147-53. doi: 10.1016/j.scitotenv.2008.08.037. Epub 2008 Oct 8.
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Plasma atrial natriuretic factor in essential hypertension: relation to cardiac size, function and systemic hemodynamics.原发性高血压患者血浆心钠素:与心脏大小、功能及体循环血流动力学的关系
J Am Coll Cardiol. 1989 Sep;14(3):715-24; discussion 725-7. doi: 10.1016/0735-1097(89)90116-2.

引用本文的文献

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Zinc, copper, and zinc- or copper-dependent enzymes in human hypertension.人体高血压中的锌、铜以及锌依赖性或铜依赖性酶
Biol Trace Elem Res. 1995 Aug-Sep;49(2-3):97-106. doi: 10.1007/BF02788959.
2
Concentrations of cadmium, lead, selenium, and zinc in human blood and seminal plasma.人体血液和精浆中镉、铅、硒和锌的浓度。
Biol Trace Elem Res. 1994 Jan;40(1):49-57. doi: 10.1007/BF02916820.