Alghamdi Bader M, Rogers Sara, Roberman Susan, Williamson Meredith, Panahi Ladan
Department of Clinical Pharmacy, Albaha College of Pharmacy, Albaha University, Al Bahah, Saudi Arabia.
Department of Pharmacy Practice, Irma Lerma Rangel School of Pharmacy, Texas A&M University, Kingsville, TX, United States.
Front Pharmacol. 2025 May 22;16:1594032. doi: 10.3389/fphar.2025.1594032. eCollection 2025.
To assess the feasibility and impact of incorporating a multidisciplinary pharmacogenomics (PGx) service within an underserved behavioral health clinic, with an emphasis on clinician perceptions.
This study was conducted in two phases at the Texas A&M Family Care Clinic. Phase one involved an online cross-sectional survey of the multidisciplinary clinic team to assess their knowledge, attitudes, and readiness for PGx integration. Phase two detailed the development and implementation of a PGx service within the Integrated Behavioral Health (IBH) clinic, outlining the workflow and collaborative approach used to offer genetic testing to eligible patients.
Of the 23 survey participants, 91% believed the PGx service would positively impact patient care, and 87% expressed interest in receiving PGx-related training. Confidence in pharmacists' ability to lead the service was reported by 65% of respondents. The primary concerns identified included cost of care, clinical utility, and potential workflow disruptions. A collaborative implementation model was developed, including preemptive and reactive testing pathways.
The implementation of a pharmacist-driven PGx service in an underserved behavioral health clinic was well-received by the clinical team and deemed feasible. While concerns regarding resources and workflow were noted, strong interest in training and multidisciplinary collaboration highlights the potential for scalable PGx service models in similar settings.
评估在服务不足的行为健康诊所引入多学科药物基因组学(PGx)服务的可行性和影响,重点关注临床医生的看法。
本研究在德克萨斯农工大学家庭护理诊所分两个阶段进行。第一阶段涉及对多学科诊所团队进行在线横断面调查,以评估他们对PGx整合的知识、态度和准备情况。第二阶段详细介绍了综合行为健康(IBH)诊所内PGx服务的开发和实施,概述了用于为符合条件的患者提供基因检测的工作流程和协作方法。
在23名调查参与者中,91%的人认为PGx服务将对患者护理产生积极影响,87%的人表示有兴趣接受与PGx相关的培训。65%的受访者表示相信药剂师有能力领导该服务。确定的主要担忧包括护理成本、临床效用和潜在的工作流程中断。开发了一种协作实施模式,包括先发制人和反应性检测途径。
临床团队对在服务不足的行为健康诊所实施由药剂师主导的PGx服务反应良好,并认为该服务可行。虽然注意到对资源和工作流程的担忧,但对培训和多学科协作的强烈兴趣凸显了在类似环境中扩展PGx服务模式的潜力。