Talloa Dario, Cordaro Simona, Attinà Giorgio, Mastrangelo Stefano, Romano Alberto, Fregola Anna, Maurizi Palma, Nanni Lorenzo, Ruggiero Antonio
Pediatric Oncology Unit, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy.
Department of Woman and Child Health and Public Health, Università Cattolica Sacro Cuore, Rome, Italy.
Case Rep Oncol Med. 2025 Jun 1;2025:8183273. doi: 10.1155/crom/8183273. eCollection 2025.
Solid pseudopapillary neoplasms (SPNs) represent a tumor of the exocrine pancreas, belonging to the group of pancreatic cystic neoplasms. It is exceedingly uncommon for SPNs to manifest in extrapancreatic locations, such as the mesocolon, greater omentum, jejunum, and ovary. SPNs are considered very rare, constituting about 0.17%-2.5% of all pancreatic neoplasms and 6% of cystic pancreatic neoplasms. We present two pediatric cases of SPNs: one involving a 16-year-old female patient and the other a 14-year-old girl, both diagnosed and treated in our center with surgical resection. The experience of our center confirms that wide margin surgery, with associated metastasectomy if necessary, represents the therapy of choice for SPNs, ensuring effective control of the disease.
实性假乳头状瘤（SPNs）是一种外分泌胰腺肿瘤，属于胰腺囊性肿瘤。SPNs发生于胰腺外部位（如结肠系膜、大网膜、空肠和卵巢）极为罕见。SPNs被认为非常罕见，约占所有胰腺肿瘤的0.17%-2.5%，占胰腺囊性肿瘤的6%。我们报告两例儿童SPNs病例：一例为16岁女性患者，另一例为14岁女孩，均在我们中心诊断并接受手术切除治疗。我们中心的经验证实，广泛切缘手术（必要时联合转移灶切除术）是SPNs的首选治疗方法，可有效控制疾病。
