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模拟胃食管反流病患者的基于聚硅氧烷-二氧化硅混合填料和释氟大块充填复合材料的体外水解降解

In Vitro Hydrolytic Degradation of Giomer-Based and Fluoride-Releasing Bulk Fill Composites Simulated for Patients with Gastroesophageal Reflux Disease.

作者信息

Aldhafyan Mohammed, Khan Rawaiz, Saeed Waseem Sharaf, Al-Odayni Abdel Basit, Asiri Rayan, Althagfan Faisal, Aldawsari Mohammed, Alneghimshi Mohammed, Alrahlah Ali

机构信息

Restorative Dental Sciences Department, College of Dentistry, King Saud University, Riyadh 11545, Saudi Arabia.

Engineer Abdullah Bugshan Research Chair for Dental and Oral Rehabilitation, College of Dentistry, King Saud University, Riyadh 11545, Saudi Arabia.

出版信息

ACS Omega. 2025 May 22;10(21):21621-21629. doi: 10.1021/acsomega.5c00784. eCollection 2025 Jun 3.

Abstract

Gastroesophageal reflux disease (GERD) often leads to tooth demineralization and degradation of dental restorations, increasing surface roughness and reducing strength. Limited studies have addressed acidic pH effects on fluoride-releasing giomer composites. This in vitro study evaluates surface roughness and flexural strength (FS) of six bulk-fill compositesSTARK, Filtek One Bulk Fill Restorative (FBF), SureFil SDR Flow (SDR), Tetric N-Ceram (TNC), X-tra fil VOCO, and Beautifil-Bulk restorative (BBR)before and after acidic exposure and abrasion caused by brushing cycles. Specimens tested included 60 disks (2 mm thick, 8 mm diameter) for surface roughness and 60 bar (25 mm × 2 mm × 2 mm) for FS. Samples were immersed in hydrochloric acid (pH 1.2) at 37 °C for 24 h, followed by 5000 brushing cycles (100 cycles/min) using medium-bristle toothbrushes. Surface roughness (Ra) and FS were measured at the baseline and post-treatment. Statistical analysis was performed by conducting Shapiro-Wilk tests, one-way ANOVA, and Tukey posthoc tests (α = 0.05). Results showed that BBR exhibited the highest increase in surface roughness after acidic exposure and brushing, followed by SDR, TNC, and VOCO. FBF and STARK demonstrated minimal changes. FS reduction was most significant in BBR (86.11 to 69.79 MPa, 18.95%) and SDR (106.78 to 88.27 MPa, 17.14%). These findings suggest that giomer-based fluoride-releasing composites, such as BBR and SDR, are susceptible to acidic degradation and brushing wear.

摘要

胃食管反流病(GERD)常导致牙齿脱矿和牙修复体降解,增加表面粗糙度并降低强度。针对酸性pH值对释氟聚硅氧烷复合树脂影响的研究有限。本体外研究评估了六种大块充填复合树脂(STARK、Filtek One Bulk Fill Restorative(FBF)、SureFil SDR Flow(SDR)、Tetric N-Ceram(TNC)、X-tra fil VOCO和Beautifil-Bulk restorative(BBR))在酸性暴露和刷牙循环引起的磨损前后的表面粗糙度和挠曲强度(FS)。测试的样本包括用于表面粗糙度测试的60个圆盘(2毫米厚,8毫米直径)和用于FS测试的60个棒材(25毫米×2毫米×2毫米)。样本在37℃下浸入盐酸(pH 1.2)中24小时,然后使用中毛牙刷进行5000次刷牙循环(100次循环/分钟)。在基线和处理后测量表面粗糙度(Ra)和FS。通过进行Shapiro-Wilk检验、单因素方差分析和Tukey事后检验(α = 0.05)进行统计分析。结果表明,BBR在酸性暴露和刷牙后表面粗糙度增加最多,其次是SDR、TNC和VOCO。FBF和STARK的变化最小。FS降低在BBR中最为显著(从86.11兆帕降至69.79兆帕,降低了18.95%),在SDR中也较为显著(从106.78兆帕降至88.27兆帕,降低了17.14%)。这些发现表明,基于聚硅氧烷的释氟复合树脂,如BBR和SDR,易受酸性降解和刷牙磨损的影响。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9c77/12138672/ea868a1012da/ao5c00784_0001.jpg

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