Beyranvand Mohammad Reza, Sheibani Mehdi, Mirzabeigi Hana, Manhoobi Hootan
Department of Cardiology, Taleghani Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Heart Views. 2024 Oct-Dec;25(4):223-228. doi: 10.4103/heartviews.heartviews_76_24. Epub 2025 May 10.
Fractional flow reserve (FFR) is used to assess the functional significance of intermediate coronary stenosis. An FFR value of 0.80 or less identifies significant lesions, whereas higher values do not require revascularization. The rate of deferred lesion revascularization (DLR) differs among studies.
This study aims to evaluate the outcome of deferring revascularization in intermediate coronary stenoses in angiography with nonischemic values in FFR assessment.
This study was conducted in a single center from March 2013 to August 2017.
The study involved patients diagnosed with moderate (50%-69%) coronary stenosis and noninfarcted FFR (>0.8). All patients were followed up, and total mortality and DLR were recorded.
Fisher exact statistical test was used to compare descriptive variables, and the Mann-Whitney statistical test was used for quantitative variables.
There were 115 patients with a mean age of 58.35 ± 10.07 years; 71 (61.7%) were male. The mean (range) follow-up period was 32 ± 15 (6-60) months. The mortality rate was 0.8%, and 4.8% of patients had revascularization during the follow-up period.
Deferring revascularization and medical management for intermediate coronary lesions with nonischemic FFR (>0.8) are a safe strategy.
血流储备分数（FFR）用于评估冠状动脉中度狭窄的功能意义。FFR值为0.80或更低表明存在显著病变，而较高的值则不需要进行血运重建。不同研究中延迟病变血运重建（DLR）的发生率有所不同。
本研究旨在评估在FFR评估中具有非缺血值的冠状动脉中度狭窄患者延迟血运重建的结果。
本研究于2013年3月至2017年8月在单一中心进行。
该研究纳入了被诊断为中度（50%-69%）冠状动脉狭窄且FFR无梗死（>0.8）的患者。所有患者均接受随访，并记录总死亡率和DLR。
采用Fisher精确检验比较描述性变量，采用Mann-Whitney检验分析定量变量。
共有115例患者，平均年龄为58.35±10.07岁；其中71例（61.7%）为男性。平均（范围）随访期为32±15（6-60）个月。死亡率为0.8%，4.8%的患者在随访期间接受了血运重建。
对于FFR无缺血（>0.8）的冠状动脉中度病变，延迟血运重建和药物治疗是一种安全的策略。
