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3. 可信结果的P值、检验效能和医学意义。

3. P values, power, and medical significance for credible results.

作者信息

Indrayan A

机构信息

Department of Clinical Research, Max Healthcare, New Delhi, India.

出版信息

J Postgrad Med. 2025 Apr 1;71(2):91-94. doi: 10.4103/jpgm.jpgm_30_25. Epub 2025 Jun 9.

Abstract

Type I and Type II errors are inherent in any empirical medical research on an antecedent-outcome relationship when it is based on a dataset of a sample of subjects. Type I error is the incorrect rejection of a true null hypothesis, and its probability in a study is the P value. This error is more serious and is kept under control by specifying a cap called the level of significance. The complement of the probability of Type II error, called power, is the probability of not missing a medically significant effect when present. This article concisely explains P values, power, and medical significance in nontechnical terms for our medical colleagues and their implications for assessing the credibility of medical research.

摘要

当基于受试者样本数据集对先行-结果关系进行任何实证医学研究时,I型错误和II型错误都是内在存在的。I型错误是对真实零假设的错误拒绝,其在研究中的概率就是P值。这种错误更为严重,通过指定一个称为显著性水平的上限来加以控制。II型错误概率的互补值,即检验效能,是指存在医学上显著效应时不遗漏它的概率。本文用通俗易懂的语言简要解释了P值、检验效能和医学显著性,以及它们对评估医学研究可信度的影响,供我们的医学同行参考。

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