Seth R K, Saini A S, Aggarwal S K
Scand J Haematol. 1985 Aug;35(2):201-4. doi: 10.1111/j.1600-0609.1985.tb01573.x.
Erythrocytes from 18 patients with chronic renal failure (CRF) and 10 healthy subjects were examined with respect to glutathione peroxidase (GSH-Px) activity and reduced glutathione (GSH) contents. The activity of GSH-Px and GSH content were found to be lower in RBC from CRF patients as compared with normal RBC. These reduced levels of GSH and GSH-Px in the red cells of uraemic patients may predispose the cells to oxidative damage.
对18例慢性肾衰竭（CRF）患者和10名健康受试者的红细胞进行了谷胱甘肽过氧化物酶（GSH-Px）活性和还原型谷胱甘肽（GSH）含量检测。结果发现，与正常红细胞相比，CRF患者红细胞中的GSH-Px活性和GSH含量较低。尿毒症患者红细胞中GSH和GSH-Px水平降低，可能使细胞易受氧化损伤。
