Erena Ayele, Benti Tsegaye, Abebe Lemi, Geleta Berhanu Bulto
Department of HIV Prevention and Control, Subeta Sub-City Health Office, Oromia, Ethiopia.
Department of Public Health, college of medicine and health science, Ambo University, Oromia, Ethiopia.
AIDS Res Ther. 2025 Jun 9;22(1):60. doi: 10.1186/s12981-025-00737-5.
Human immunodeficiency virus self-testing (HIVST) using oral fluid is the best way to receive preventive and treatment services, which helps lower morbidity and mortality related to the problem.
To assess the acceptance and associated factors of human immunodeficiency virus self-testing using oral fluid among targeted adult clients at public health facilities in Sheger City, Ethiopia in 2023.
An institution-based cross-sectional study was conducted from July 1 to 30, 2023 among clients visiting health facilities for Voluntary counseling and testing (VCT), Provider-initiated counseling and testing (PICT), and Prevention of mother-to-child transmission (PMTCT) services. A total of 317 study participants were selected using a systematic random sampling method. A structured questionnaire was used to collect data from the clients through interviews. Clients were asked to use HIVST using oral fluid when they came for HIV testing at the VCT, PICT, and PMTCT services, and those responded 'yes' to the question "will you accept HIVST using oral fluid today?", were considered as acceptors. Data were analyzed using bivariate and multivariable binary logistic regression. Variables with a p-value of < 0.25 in bivariate analysis, were candidates for multivariable analysis. Adjusted odds ratios (AOR) with 95% confidence intervals (CI) were calculated to identify the presence and strength of association.
In total, 314 study participants were involved making a response rate of 99.1%. The overall acceptance of human immunodeficiency virus self-testing (HIVST) among targeted adult clients attending public health facilities in the study area was 169 (53.8%) (95%CI: 48.1%, 59.2%). Being married (AOR = 3.97; 95%CI: 1.74, 9.05), having fear of being stigmatized (AOR = 3.75; 95%CI: 1.64, 8.61), obtaining counseling during HIV testing (AOR = 3.33; 95%CI: 1.28, 8.64) and not sure about confidential information related to HIV testing (AOR = 2.49; 95%CI: 1.13, 5.46) were factors that were significantly associated with acceptance of HIVST using oral fluid.
This study found that acceptance of HIVST among targeted adults in public health facilities was consistent with global findings. Factors such as being married, fear of stigma, receiving counseling, and concerns about confidentiality were significantly associated with HIVST acceptance. Addressing these factors can help increase HIVST acceptance.
使用口腔液进行人类免疫缺陷病毒自我检测（HIVST）是获得预防和治疗服务的最佳方式，有助于降低与该问题相关的发病率和死亡率。
评估2023年埃塞俄比亚谢格尔市公共卫生机构中目标成年客户对使用口腔液进行人类免疫缺陷病毒自我检测的接受情况及相关因素。
2023年7月1日至30日，在前往卫生机构接受自愿咨询检测（VCT）、提供者发起的咨询检测（PICT）和预防母婴传播（PMTCT）服务的客户中开展了一项基于机构的横断面研究。采用系统随机抽样方法共选取了317名研究参与者。通过访谈使用结构化问卷从客户处收集数据。当客户前来进行VCT、PICT和PMTCT服务的HIV检测时，要求他们使用口腔液进行HIVST，对“你今天会接受使用口腔液进行HIVST吗？”这个问题回答“是”的人被视为接受者。数据采用双变量和多变量二元逻辑回归进行分析。在双变量分析中p值<0.25的变量是多变量分析的候选变量。计算调整后的优势比（AOR）及95%置信区间（CI）以确定关联的存在和强度。
共有314名研究参与者参与，回复率为99.1%。在研究区域内前往公共卫生机构的目标成年客户中，人类免疫缺陷病毒自我检测（HIVST）的总体接受率为169人（53.8%）（95%CI：48.1%，59.2%）。已婚（AOR = 3.97；95%CI：1.74，9.05）、担心被污名化（AOR = 3.75；95%CI：1.64，8.61）、在HIV检测期间接受咨询（AOR = 3.33；95%CI：1.28，8.64）以及不确定与HIV检测相关的保密信息（AOR = 2.49；95%CI：1.13，5.46）是与接受使用口腔液进行HIVST显著相关的因素。
本研究发现，公共卫生机构中目标成年人对HIVST的接受情况与全球研究结果一致。已婚、担心污名化、接受咨询以及对保密性的担忧等因素与HIVST接受情况显著相关。解决这些因素有助于提高对HIVST的接受度。
