Department of Epidemiology and Health Statistics, School of Public Health and Management, Chongqing Medical University, Chongqing 400016, China.
The Second Clinical College, Chongqing Medical University, Chongqing 400016, China.
Int J Environ Res Public Health. 2020 Mar 3;17(5):1634. doi: 10.3390/ijerph17051634.
While studies on human immunodeficiency virus self-testing (HIVST) continue to accumulate after the World Health Organization's recommendation of HIVST as an additional approach to HIV testing services in 2016, few studies have focused on men who have sex with men (MSM) in Chinese cities. A cross-sectional study was conducted to describe the HIVST status of MSM in Chongqing, China. MSM participants were recruited by random sampling, and qualified interviewers collected data, using confidential self-administered questionnaires. Blood specimens were collected for HIV antibody detection. The survey evaluated the uptake and accuracy of HIVST kits and identified factors that may be associated with HIVST. The proportion of HIVST uptake was 15.6%. The sensitivity and specificity of HIVST were 74.2% (95% confidence interval [CI] 66.6%-80.7%) and 99.0% (95% CI 96.9%-99.7%), respectively. The consistency between the HIVST kit and antibody detection results was 90.5% (95% CI 87.5%-93.0%), and the Kappa value was 0.777 ( < 0.001). The positive predictive value of self-testing kits is 80.9% and the negative predictive value is 17.7%. Having been tested ≥2 times in the last year, higher educational levels, and higher scores of basic HIV/AIDS knowledge facilitated higher uptake of HIVST. Self-reported existing barriers for HIVST uptake included older age, marital status, and having resided in Chongqing for more than two years.
虽然自世界卫生组织在 2016 年推荐 HIVST 作为 HIV 检测服务的另一种方法以来,关于人类免疫缺陷病毒自检(HIVST)的研究不断增加,但很少有研究关注中国城市的男男性行为者(MSM)。本研究采用横断面研究方法,描述了中国重庆市 MSM 的 HIVST 状况。通过随机抽样招募 MSM 参与者,合格的访谈员使用保密的自我管理问卷收集数据。采集血样进行 HIV 抗体检测。调查评估了 HIVST 试剂盒的采用情况和准确性,并确定了可能与 HIVST 相关的因素。HIVST 的采用率为 15.6%。HIVST 的灵敏度和特异性分别为 74.2%(95%置信区间 [CI] 66.6%-80.7%)和 99.0%(95% CI 96.9%-99.7%)。HIVST 试剂盒与抗体检测结果的一致性为 90.5%(95% CI 87.5%-93.0%),Kappa 值为 0.777(<0.001)。自检试剂盒的阳性预测值为 80.9%,阴性预测值为 17.7%。在过去一年中接受过≥2 次检测、较高的教育水平和较高的基本 HIV/AIDS 知识得分有助于提高 HIVST 的采用率。自我报告的 HIVST 采用障碍包括年龄较大、婚姻状况和在重庆居住时间超过两年。