Jain Samriddhi, Agrawal Amit, Sharma Shweta, Chinnadurai Ramkumar
Department of Pediatrics, Gandhi Medical College, Bhopal 462022, Madhya Pradesh, India.
World J Clin Pediatr. 2025 Jun 9;14(2):103377. doi: 10.5409/wjcp.v14.i2.103377.
Malnutrition among patients admitted to a pediatric intensive care unit (PICU) is common. However, there is a lack of data on its impact on the critically ill.
To assess the impact of nutritional status on the outcome of critically ill children admitted to PICU.
This observational study was conducted in a tertiary care teaching institute for one year, including 210 children aged 1 month to 14 years admitted to a 15-bed PICU for a minimum of 24 hours. Patients with less than 24 hours of PICU stay, who received palliative care, or with syndromic short stature were excluded. Relevant data were collected including anthropometric details, demographic data, duration of mechanical ventilation (MV), PICU, and hospital stay and outcome. Malnourished and well-nourished groups were compared using an independent -test, one-way analysis of variance, and test.
Among 210 patients, there were 129 males and 81 females. There were 57 (27.1%) children less than 6 months of age, 95 (45.2%) between 6 months and 5 years, and 58 (27.6%) more than 5 years of age. The prevalence of malnutrition in the study sample was 51.9% ( = 109). The overall mortality was 22.9% (48/210), 26.6% (29/109) among malnourished, and 18.8% (19/101) among well-nourished children ( = 0.241). A significant association was found between the severity of malnutrition and duration of MV ( = 0.001), PICU stay ( = 0.001), and hospital stay ( = 0.021).
Malnutrition is common in critically ill children and contributes to poor clinical outcomes such as duration of MV, PICU, and hospital stay. However, mortality was comparable in both groups.
入住儿科重症监护病房(PICU)的患者中营养不良很常见。然而,关于其对危重症患者影响的数据却很缺乏。
评估营养状况对入住PICU的危重症儿童预后的影响。
这项观察性研究在一家三级医疗教学机构进行了一年,纳入了210名年龄在1个月至14岁之间、入住拥有15张床位的PICU至少24小时的儿童。排除PICU住院时间少于24小时、接受姑息治疗或患有综合征性身材矮小的患者。收集了相关数据,包括人体测量细节、人口统计学数据、机械通气(MV)持续时间、PICU和住院时间以及预后情况。采用独立样本t检验、单因素方差分析和卡方检验对营养不良组和营养良好组进行比较。
210例患者中,男性129例,女性81例。年龄小于6个月的儿童有57例(27.1%),6个月至5岁的有95例(45.2%),5岁以上的有58例(27.6%)。研究样本中营养不良的患病率为51.9%(n = 109)。总体死亡率为22.9%(48/210),营养不良儿童中为26.6%(29/109),营养良好儿童中为18.8%(19/101)(P = 0.241)。发现营养不良的严重程度与MV持续时间(P = 0.001)、PICU住院时间(P = 0.001)和住院时间(P = 0.021)之间存在显著关联。
营养不良在危重症儿童中很常见,并导致诸如MV持续时间、PICU住院时间和住院时间等不良临床结局。然而,两组的死亡率相当。