Dabla Pradeep K, Dabas Aashima
Department of Biochemistry, Govind Ballabh Pant Institute of Postgraduate Education and Research, Associated Maulana Azad Medical College, New Delhi 110002, Delhi, India.
Department of Pediatrics, Maulana Azad Medical College and associated Lok Nayak Hospital, New Delhi 110002, Delhi, India.
World J Crit Care Med. 2025 Jun 9;14(2):100623. doi: 10.5492/wjccm.v14.i2.100623.
The advent of point-of-care testing (POCT) has revolutionized the approach to patient management, especially for pediatric care. POCT provides rapid, on-the-spot biochemical and microbiological evaluations, bypassing delays typically associated with central laboratory testing, enabling swift clinical decision-making. Additionally, POCT has proven to be a valuable prognostic tool for monitoring electrolyte, lactate, creatinine levels, often a marker of severe illness and poor outcomes. POCT enables its faster identification, allowing for prompt interventions. This capability is essential in managing conditions like sepsis, where timely treatment can significantly impact survival rates. However, the implementation of POCT is not without its challenges. Variability in sample handling, particularly with heparinized syringes, can affect the accuracy of certain measurements, such as potassium levels. The absence of comprehensive follow-up data and cost-effectiveness analyses in some studies indicate the need for continued research to optimize the use of POCT. In conclusion, POCT is a transformative tool in critical care, offering prompt and reliable assessments that significantly enhance patient management. As technology advances, the integration of POCT into emergency departments and intensive critical care units holds great promise for improving the quality of healthcare and patient survival rates.
即时检验(POCT)的出现彻底改变了患者管理的方式,尤其是在儿科护理方面。POCT提供快速的现场生化和微生物评估,避免了通常与中心实验室检测相关的延迟,从而能够迅速做出临床决策。此外,POCT已被证明是一种有价值的预后工具,可用于监测电解质、乳酸、肌酐水平,这些指标通常是严重疾病和不良预后的标志。POCT能够更快地识别这些情况,以便及时进行干预。这种能力在管理败血症等病症时至关重要,因为及时治疗会对生存率产生重大影响。然而,POCT的实施并非没有挑战。样本处理的变异性,特别是使用肝素化注射器时,会影响某些测量的准确性,如钾水平。一些研究中缺乏全面的随访数据和成本效益分析,这表明需要继续进行研究以优化POCT的使用。总之,POCT是重症护理中的一种变革性工具,提供及时且可靠的评估,显著增强了患者管理。随着技术的进步,将POCT整合到急诊科和重症监护病房有望极大地提高医疗质量和患者生存率。