da Paz Clarissa Araujo, Eiró-Quirino Luciana, de Araújo Daniella Bastos, Hartcopff Priscille Fidelis Pacheco, Dos Santos Murilo Farias, da Cunha Ferreira Rayllan, da Silva Deiga Yris, de Sousa Barbosa Anara, de Souza Luana Vasconcelos, Hamoy Maria Klara Otake, Barbosa Gabriela Brito, do Prado Alejandro Ferraz, Rodrigues Keuri Eleutério, Barbas Luis André Luz, Muto Nilton Akio, Hamoy Moisés
Laboratory of Pharmacology and Natural Products Toxicology, ICB/UFPA, Belém, PA, Brazil.
Laboratory of Pharmacology and Toxicology of Cardiovascular System, ICB/UFPA, Belém, PA, Brazil.
Environ Sci Pollut Res Int. 2025 May;32(25):15403-15414. doi: 10.1007/s11356-025-36524-y. Epub 2025 Jun 10.
Pollution from gold mining has been a major problem in the Amazon River basin. Mercury in its main organic form, methylmercury (MeHg), is potentially toxic to fish, which are mainly affected by inadequate disposal of this pollutant. The present study aimed to evaluate the cardiac graphoelements over the 1-h exposure of Colossoma macropomum to an immersion bath using different concentrations of MeHg. For that purpose, 45 fish were used, assayed into four groups according to the following concentrations: 10 µg/ml, 20 µg/ml, 30 µg/ml and 40 µg/ml MeHg (n = 9). Exposure to different concentrations of MeHg demonstrated the triggering of arrhythmia over the time, and higher concentrations (30 and 40 µg/ml) had deleterious cardiac effects, with atrioventricular block. Such effects became more severe depending on the length of the exposure time to MeHg, demonstrating the susceptibility of tambaqui fish C. macropomum to this intoxication.
金矿开采造成的污染一直是亚马孙河流域的一个主要问题。汞的主要有机形态甲基汞（MeHg）对鱼类具有潜在毒性，鱼类主要受到这种污染物处置不当的影响。本研究旨在评估巨脂鲤暴露于不同浓度甲基汞的浸泡浴中1小时后的心电图要素。为此，使用了45条鱼，根据以下浓度分为四组：10微克/毫升、20微克/毫升、30微克/毫升和40微克/毫升甲基汞（n = 9）。暴露于不同浓度的甲基汞显示随着时间推移会引发心律失常，较高浓度（30和40微克/毫升）具有有害的心脏效应，伴有房室传导阻滞。根据暴露于甲基汞的时间长短，这些效应会变得更加严重，表明淡水鲳鱼巨脂鲤对这种中毒很敏感。
