Akiba T, Yoshikawa M, Kinoda M, Otaki S, Ishii K, Kobayashi Y, Sato T
Tohoku J Exp Med. 1985 Jul;146(3):313-20. doi: 10.1620/tjem.146.313.
Left (LV) and right ventricular (RV) volume data were obtained from biplane cineangiocardiograms in 31 patients with Kawasaki disease who showed normal coronary arteries in selective coronary arteriograms. LV and RV volumes were calculated by using Simpson's rule method. Both of end-diastolic (EDV) and stroke volume (SV) were excellently expressed as a function of body surface area (BSA) with exponential relationship: LVEDV = 104.3 (BSA)1.61 ml (r = 0.93, p less than 0.001), RVEDV = 109.7 (BSA)1.68 ml (r = 0.90, p less than 0.001), LVSV = 68.1 (BSA)1.60 ml (r = 0.89, p less than 0.001) and RVSV = 66.8 (BSA)1.76 ml (r = 0.86, p less than 0.001). LV ejection fraction (LVEF) averaged 66 +/- 1% (mean +/- S.E.) and RVEF 58 +/- 1%. Both of them showed no significant correlations with BSA. The normal values of EDV and SV in infants and children can be predicted from their BSA by using the exponential equations demonstrated by the present study. Thus, these values in pediatric patients with heart diseases could be evaluated in terms of percentage of normal.
从31例川崎病患者的双平面心血管造影中获取左心室（LV）和右心室（RV）容积数据，这些患者在选择性冠状动脉造影中显示冠状动脉正常。采用Simpson法则计算LV和RV容积。舒张末期容积（EDV）和每搏输出量（SV）均与体表面积（BSA）呈良好的指数函数关系：左心室舒张末期容积（LVEDV）=104.3（BSA）^1.61ml（r=0.93，p<0.001），右心室舒张末期容积（RVEDV）=109.7（BSA）^1.68ml（r=0.90，p<0.001），左心室每搏输出量（LVSV）=68.1（BSA）^1.60ml（r=0.89，p<0.001），右心室每搏输出量（RVSV）=66.8（BSA）^1.76ml（r=0.86，p<0.001）。左心室射血分数（LVEF）平均为66±1%（均值±标准误），右心室射血分数（RVEF）为58±1%。两者均与BSA无显著相关性。通过本研究所示的指数方程，可根据婴儿和儿童的BSA预测其EDV和SV的正常值。因此，对于患有心脏病的儿科患者，这些值可以用正常百分比来评估。
