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Longitudinal Measurement of Serum Neurofilament Light Chain in Patients With CADASIL.

作者信息

Lee Jung Seok, Kang Ji-Hoon, Kang Chul-Hoo, Kim Joong-Goo, Seo Sang Won, Park Yu Hyun, Yun Jihwan, Yun So Young, Choi Jay Chol

机构信息

Department of Neurology, Jeju National University Hospital, Jeju National University College of Medicine, Jeju, Korea.

Department of Neurology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.

出版信息

J Stroke. 2025 May;27(2):261-265. doi: 10.5853/jos.2024.05666. Epub 2025 May 31.

DOI:10.5853/jos.2024.05666
PMID:40494586
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12152448/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2306/12152448/a5ddeb5c93e6/jos-2024-05666f3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2306/12152448/e72deec2695d/jos-2024-05666f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2306/12152448/2a3e288c51a7/jos-2024-05666f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2306/12152448/a5ddeb5c93e6/jos-2024-05666f3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2306/12152448/e72deec2695d/jos-2024-05666f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2306/12152448/2a3e288c51a7/jos-2024-05666f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2306/12152448/a5ddeb5c93e6/jos-2024-05666f3.jpg

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Longitudinal Measurement of Serum Neurofilament Light Chain in Patients With CADASIL.伴有皮质下梗死和白质脑病的常染色体显性遗传性脑动脉病(CADASIL)患者血清神经丝轻链的纵向测量
J Stroke. 2025 May;27(2):261-265. doi: 10.5853/jos.2024.05666. Epub 2025 May 31.
2
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本文引用的文献

1
Neurofilament Light Chain as a Biomarker in Cerebral Small-Vessel Disease.神经丝轻链作为脑小血管病的生物标志物
Mol Diagn Ther. 2022 Jan;26(1):1-6. doi: 10.1007/s40291-021-00566-y. Epub 2021 Nov 25.
2
Eighteen-Year Disease Progression and Survival in CADASIL.伴有皮质下梗死和白质脑病的常染色体显性遗传性脑动脉病(CADASIL)的18年疾病进展与生存情况
J Stroke. 2021 Jan;23(1):132-134. doi: 10.5853/jos.2020.04112. Epub 2021 Jan 31.
3
Neurofilament light chain predicts future dementia risk in cerebral small vessel disease.神经丝轻链可预测脑小血管病患者未来患痴呆症的风险。
J Neurol Neurosurg Psychiatry. 2021 Feb 8;92(6):582-9. doi: 10.1136/jnnp-2020-325681.
4
Association of Plasma Neurofilament Light With Small Vessel Disease Burden in Nondemented Elderly: A Longitudinal Study.血浆神经丝轻链与非痴呆老年人小血管病负担的相关性:一项纵向研究。
Stroke. 2021 Mar;52(3):896-904. doi: 10.1161/STROKEAHA.120.030302. Epub 2021 Feb 1.
5
Plasma neurofilament light chain and glial fibrillary acidic protein predict stroke in CADASIL.血浆神经丝轻链和胶质纤维酸性蛋白可预测 CADASIL 中的卒中。
J Neuroinflammation. 2020 Apr 22;17(1):124. doi: 10.1186/s12974-020-01813-5.
6
Serum Neurofilament light correlates with CADASIL disease severity and survival.血清神经丝轻链与 CADASIL 病严重程度和生存相关。
Ann Clin Transl Neurol. 2018 Nov 20;6(1):46-56. doi: 10.1002/acn3.678. eCollection 2019 Jan.
7
Serum Neurofilament Light Chain Levels Are Related to Small Vessel Disease Burden.血清神经丝轻链水平与小血管疾病负担相关。
J Stroke. 2018 May;20(2):228-238. doi: 10.5853/jos.2017.02565. Epub 2018 May 31.
8
Clinical correlates of longitudinal MRI changes in CADASIL.CADASIL 患者纵向 MRI 变化的临床相关性。
J Cereb Blood Flow Metab. 2019 Jul;39(7):1299-1305. doi: 10.1177/0271678X18757875. Epub 2018 Feb 5.
9
Serum neurofilament light is sensitive to active cerebral small vessel disease.血清神经丝轻链对活动性脑小血管病敏感。
Neurology. 2017 Nov 14;89(20):2108-2114. doi: 10.1212/WNL.0000000000004645. Epub 2017 Oct 18.
10
Subcortical lacunar lesions: an MR imaging finding in patients with cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy.皮质下腔隙性病变:常染色体显性遗传性脑动脉病伴皮质下梗死和白质脑病患者的磁共振成像表现
Radiology. 2002 Sep;224(3):791-6. doi: 10.1148/radiol.2243011123.