Resta L, Micheau C, Cimmino A
Tumori. 1985 Aug 31;71(4):361-5. doi: 10.1177/030089168507100407.
The role in tumor spread and the prognostic value of metastasis in a prelaryngeal node were investigated in 124 cases of laryngeal and hypopharyngeal carcinoma selected from about 900 total laryngectomies and pharyngolaryngectomies. Metastasis in a prelaryngeal node was noted in 26 cases: 22 without capsular rupture (N+) and 4 with capsular rupture (N+R+). Vascular embolism (E+) was never noted. Patients with a metastatic prelaryngeal node had a tumor of the piriform sinus in 13 cases (50%), a transglottic tumor in 6, glotto-subglottic in 3, glottic in 2 and supraglottic in 2. They also more frequently had involvement of the cervical nodes (81%) and of the thyroid gland. The 5-year survival in these patients is very poor: only 3 patients (11.5%) were alive and free of disease. These data demonstrate the role of prelaryngeal nodes in tumors that affect the hypopharynx and the antero-inferior portion of the larynx and that directly reach this node through the anterior lymphatic peduncle.
从约900例全喉切除术和咽喉切除术患者中选取124例喉癌和下咽癌患者，研究喉前淋巴结在肿瘤扩散中的作用及转移的预后价值。26例患者出现喉前淋巴结转移：22例无包膜破裂（N+），4例有包膜破裂（N+R+）。未发现血管栓塞（E+）。发生喉前淋巴结转移的患者中，13例（50%）为梨状窝肿瘤，6例为跨声门肿瘤，3例为声门-声门下肿瘤，2例为声门肿瘤，2例为声门上肿瘤。他们的颈部淋巴结（81%）和甲状腺受累也更为常见。这些患者的5年生存率非常低：只有3例（11.5%）存活且无疾病。这些数据证明了喉前淋巴结在影响下咽和喉前下部分的肿瘤中的作用，这些肿瘤通过前淋巴蒂直接到达该淋巴结。
