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院外创伤性心脏骤停的人口统计学、管理及结局:一项比较儿童和成人的回顾性队列研究

Demographics, management, and outcomes of out-of-hospital traumatic cardiac arrest: a retrospective cohort study comparing children and adults.

作者信息

Morcel Baptiste, Mercier Eric, Debaty Guillaume, David Jean-Stéphane, Javouhey Etienne, Baert Valentine, Gossiome Amaury, Desmeules Francis, Cournoyer Alexis, Tazarourte Karim, Benhamed Axel

机构信息

Service SAMU-Urgences, Centre Hospitalier Universitaire Édouard Herriot, Hospices Civils de Lyon, Lyon, France.

Centre de recherche, CHU de Québec-Université Laval, Québec, Québec, Canada.

出版信息

Resusc Plus. 2025 May 10;24:100981. doi: 10.1016/j.resplu.2025.100981. eCollection 2025 Jul.

Abstract

AIM

Out-of-hospital traumatic cardiac arrests (TCA) are associated with a poor prognosis, yet limited research focuses on paediatric TCA. This study aimed to compare outcomes following TCA between children and adults.

METHODS

We conducted a retrospective cohort study using data from the French cardiac arrest registry (RéAC) between July 2011 and March 2023. We included all patients under 65 years who suffered a TCA managed by a mobile medical team. Patients were categorized as children (<18 years) and adults (18-65 years). The primary endpoint was the 30-day survival, and secondary endpoints were: return of spontaneous circulation (ROSC), survival at hospital admission and survival with a favourable neurological outcome (Cerebral Performance Categories 1-2) at 30 days.

RESULTS

Among 5,030 included patients, 396 were children (median age 13 [IQR 4-16] years; 73.2% male) and 4,634 were adults (median age 39 [IQR 27-51] years; 80.4% male). Paediatric patients had significantly higher rates of ROSC (25.5% vs. 20.6%,  = 0.02), survival to hospital admission (21.2% vs. 14.7%,  < 0.001), and 30-day survival (3.5% vs. 1.6%,  < 0.01). However, the proportion of patients achieving a favourable neurological outcome at 30 days did not differ significantly between groups (0.8% vs. 0.9%,  = 0.80).

CONCLUSIONS

Paediatric patients with out-of-hospital TCA demonstrate higher rates of ROSC and survival compared to adults, although neurological outcomes remain poor in both populations. These findings underscore age-related disparities in TCA prognosis and highlight the need for age-specific research in TCA patients.

摘要

目的

院外创伤性心脏骤停(TCA)预后较差,但针对儿童TCA的研究有限。本研究旨在比较儿童和成人TCA后的结局。

方法

我们使用2011年7月至2023年3月法国心脏骤停登记处(RéAC)的数据进行了一项回顾性队列研究。我们纳入了所有65岁以下由移动医疗团队处理的TCA患者。患者分为儿童(<18岁)和成人(18 - 65岁)。主要终点是30天生存率,次要终点包括:自主循环恢复(ROSC)、入院时存活以及30天时具有良好神经功能结局(脑功能分类1 - 2级)的存活情况。

结果

在纳入的5030例患者中,396例为儿童(中位年龄13岁[四分位间距4 - 16岁];73.2%为男性),4634例为成人(中位年龄39岁[四分位间距27 - 51岁];80.4%为男性)。儿科患者的ROSC发生率显著更高(25.5%对20.6%,P = 0.02)、入院时存活率(21.2%对14.7%,P < 0.001)以及30天生存率(3.5%对1.6%,P < 0.01)。然而,两组在30天时达到良好神经功能结局的患者比例无显著差异(0.8%对0.9%,P = 0.80)。

结论

与成人相比,院外TCA的儿科患者ROSC率和生存率更高,尽管两组的神经功能结局均较差。这些发现强调了TCA预后中与年龄相关的差异,并突出了针对TCA患者进行特定年龄研究的必要性。

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本文引用的文献

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