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[病毒唑与金刚烷胺对A(H3N2)和B型流感病毒感染患者治疗效果的比较评估]

[Comparative evaluation of the therapeutic effectiveness of virazole and remantadine in patients with influenza caused by A(H3N2) and B viruses].

作者信息

Kolobukhina L V, Krylov V F, Grushinskaia I A, Ivanova L A, Poliakova T G

出版信息

Vopr Virusol. 1985 May-Jun;30(3):296-8.

PMID:4049841
Abstract

Therapeutic effectiveness of virazole in treatment of patients with influenza caused by A (H3N2) and B viruses (1980-1984) was demonstrated in 432 patients with the laboratory-confirmed diagnosis of influenza. Provided the treatment started on the 1st day of the disease, the experimental group showed normalization of fever and regression of toxicity symptoms within shorter periods than the controls. However in treatment of patients with influenza caused by A (H3N2) virus virazole showed a less marked therapeutic effect than the Soviet antiinfluenza drug, remantadine.

摘要

1980年至1984年间,432例经实验室确诊为流感的患者证实了病毒唑对由A(H3N2)和B型病毒引起的流感患者的治疗效果。如果在疾病的第一天开始治疗,与对照组相比,实验组发热恢复正常和毒性症状消退的时间更短。然而,在治疗由A(H3N2)病毒引起的流感患者时,病毒唑的治疗效果不如苏联的抗流感药物金刚烷胺显著。

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