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肋骨骨折患者呼吸困难的危险因素:一项关于患者报告结局的前瞻性研究。

Risk Factors for Dyspnea in Rib Fracture Patients: A Prospective Study of Patient-Reported Outcomes.

作者信息

Switalla Kayla M, Sundlof Madison, Jones Emma, Bahr Matthew, Doering Michael, Martin David, McCormick-Deaton John, Melton-Meaux Genevieve B, Tignanelli Christopher

机构信息

University of Minnesota Medical School, Minneapolis, Minnesota.

University of Minnesota Medical School, Minneapolis, Minnesota.

出版信息

J Surg Res. 2025 Aug;312:15-24. doi: 10.1016/j.jss.2025.05.005. Epub 2025 Jun 10.

Abstract

INTRODUCTION

Rib fractures are common and associated with significant morbidity and mortality. Despite treatment advances, knowledge gaps persist regarding optimization of rib fracture outcomes, particularly for symptoms such as dyspnea post discharge. This study examined the frequency and severity of dyspnea-related patient-reported outcome measures (PROMs) in rib fracture patients.

METHODS

From 2021 to 2022, patients presenting with rib fractures at a Midwest health system used a mobile platform to track PROMs after discharge. Our primary outcome was early dyspnea, defined as dyspnea symptoms within 2 wk (d 4-14) post discharge. We categorized dyspnea as none/mild (scores <4) or moderate/severe (scores ≥4). Multivariable logistic regressions were developed to assess factors associated with more severe dyspnea.

RESULTS

Of the 1103 rib fracture patients during our study period, dyspnea-related PROMs were collected on 98 patients within 2 wk post discharge. Of these respondents, 41.8% reported experiencing moderate/severe early dyspnea. Multivariable logistic regression showed that older age (odds ratio [OR], 0.97; 95% confidence interval [CI], 0.94-0.99; P = 0.048) was associated with lower odds for moderate/severe early dyspnea at 2 wk post discharge, while the need for opioid pain management on admission (OR, 3.8; 95% CI, 1.3-10.5; P = 0.01) and medical history of asthma (OR, 5.7; 95% CI, 1.4-22.2; P = 0.01) were associated with significantly increased odds of moderate/severe early dyspnea.

CONCLUSIONS

We demonstrate the utility and feasibility of remote patient monitoring for characterizing and monitoring post discharge dyspnea symptoms using PROMs. Notably, risk factors such as age, opioid pain management on admission, and asthma history influence the severity of early dyspnea in rib fracture patients. These findings highlight the potential value of utilizing PROMs to help evaluate optimal post discharge follow-up for rib fracture patients.

摘要

引言

肋骨骨折很常见,且与较高的发病率和死亡率相关。尽管治疗取得了进展,但在肋骨骨折治疗效果的优化方面仍存在知识空白,尤其是对于出院后呼吸困难等症状。本研究调查了肋骨骨折患者中与呼吸困难相关的患者报告结局指标(PROMs)的频率和严重程度。

方法

2021年至2022年期间,美国中西部一家医疗系统中出现肋骨骨折的患者在出院后使用移动平台跟踪PROMs。我们的主要结局是早期呼吸困难,定义为出院后2周内(第4至14天)出现的呼吸困难症状。我们将呼吸困难分为无/轻度(评分<4)或中度/重度(评分≥4)。我们建立了多变量逻辑回归模型,以评估与更严重呼吸困难相关的因素。

结果

在我们的研究期间,1103例肋骨骨折患者中,98例患者在出院后2周内收集了与呼吸困难相关的PROMs。在这些受访者中,41.8%报告经历了中度/重度早期呼吸困难。多变量逻辑回归显示,年龄较大(优势比[OR],0.97;95%置信区间[CI],0.94 - 0.99;P = 0.048)与出院后2周出现中度/重度早期呼吸困难的较低几率相关,而入院时需要阿片类药物止痛治疗(OR,3.8;95%CI,1.3 - 10.5;P = 0.01)和哮喘病史(OR,5.7;95%CI,1.4 - 22.2;P = 0.01)与中度/重度早期呼吸困难的几率显著增加相关。

结论

我们证明了使用PROMs进行远程患者监测以表征和监测出院后呼吸困难症状的实用性和可行性。值得注意的是,年龄、入院时的阿片类药物止痛治疗和哮喘病史等风险因素会影响肋骨骨折患者早期呼吸困难的严重程度。这些发现凸显了利用PROMs来帮助评估肋骨骨折患者出院后最佳随访的潜在价值。

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