Agarwal Siddharth, Elbenawi Hossam, Patel Harsh P, Asad Zain Ul Abideen, Munir Muhammad Bilal, Kowlgi Gurukripa N, Lee Justin Z, Tan Nicholas Y, Sugrue Alan, Friedman Paul A, Asirvatham Samuel J, DeSimone Daniel C, Mulpuru Siva K, Cha Yong-Mei, Deshmukh Abhishek, DeSimone Christopher V
Department of Cardiovascular Medicine, Mayo Clinic, Rochester, Minnesota, USA.
Department of Cardiology, Southern Illinois University School of Medicine, Springfield, Illinois, USA.
J Cardiovasc Electrophysiol. 2025 Aug;36(8):1938-1947. doi: 10.1111/jce.16758. Epub 2025 Jun 11.
Transvenous lead removal (TLR) is a Class I indication for patients with cardiac implantable electronic device (CIED) infections. However, disparities in the utilization of TLR have not been fully explored, particularly concerning demographic and socioeconomic factors.
This study aims to examine whether disparities exist among patients hospitalized for CIED infections with respect to the utilization of TLR, focusing on sex, race, and income characteristics.
We utilized the 2019 National Inpatient Sample (NIS) to assess patients hospitalized with CIED infections and identify those who underwent TLR. Multiple logistic regression was used to examine risk factors for TLR utilization, including age, sex, race/ethnicity, and socioeconomic characteristics.
A total of 56 709 patients were hospitalized for CIED infection in the United States in 2019, of which 9867 (17.4%) underwent TLR. On an adjusted analysis, females and Black patients were found to have lower odds of undergoing TLR compared to males and White patients (OR: 0.62; 95% CI: 0.59-0.78; p < 0.01; and OR: 0.47; 95% CI: 0.39-0.57; p < 0.01, respectively). Hispanic patients also had reduced odds of TLR (OR: 0.73; 95% CI: 0.58-0.93; p = 0.01). No significant associations were observed between income or insurance status and the likelihood of receiving TLR after adjustment.
This study identified significant disparities in the utilization of TLR among patients hospitalized for CIED infections. Female, Black, and Hispanic patients were significantly less likely to receive TLR.
经静脉导线拔除术(TLR)是心脏植入式电子设备(CIED)感染患者的I类适应症。然而,TLR使用方面的差异尚未得到充分研究,尤其是在人口统计学和社会经济因素方面。
本研究旨在探讨因CIED感染住院的患者在TLR使用方面是否存在差异,重点关注性别、种族和收入特征。
我们利用2019年全国住院患者样本(NIS)评估因CIED感染住院的患者,并确定接受TLR的患者。采用多因素逻辑回归分析TLR使用的危险因素,包括年龄、性别、种族/民族和社会经济特征。
2019年美国共有56709例因CIED感染住院的患者,其中9867例(17.4%)接受了TLR。经校正分析发现,与男性和白人患者相比,女性和黑人患者接受TLR的几率较低(OR:0.62;95%CI:0.59-0.78;p<0.01;以及OR:0.47;95%CI:0.39-0.57;p<0.01)。西班牙裔患者接受TLR的几率也降低(OR:0.73;95%CI:0.58-0.93;p=0.01)。校正后未观察到收入或保险状况与接受TLR可能性之间的显著关联。
本研究发现因CIED感染住院的患者在TLR使用方面存在显著差异。女性、黑人和西班牙裔患者接受TLR的可能性显著较低。