Pan Jiaxin, Jia Yanbing, Li Kuicheng, Liu Xiaoyan, Liu Zhichao, Cui Zhenyang, Liao Linrong, Diao Yingxiu, Liu Hao
School of Rehabilitation Medicine, Shandong Second Medical University, Weifang, China.
School of Rehabilitation Medicine, Gannan Medical University, Ganzhou, Jiangxi Province, China.
Eur J Phys Rehabil Med. 2025 Jun;61(3):572-582. doi: 10.23736/S1973-9087.25.08442-4. Epub 2025 Jun 12.
Repetitive peripheral magnetic stimulation (rPMS) is a non-invasive and painless approach developed for therapeutic intervention in clinical rehabilitation. Chronic musculoskeletal pain (CMP) originates from the musculoskeletal system and leads to disability and fear of pain. It may be an option for CMP treatment, but its effectiveness is still unclear.
PubMed, PEDro, the Cochrane Library, Web of Science, and Embase were searched for relevant literatures according to strict inclusion and exclusion criteria on May 26, 2023.
The methodology quality of the included studies was assessed using the Cochrane Collaboration's Risk of Bias tool (ROB 2.0) and the GRADE (Grading of Recommendations, Assessment, Development, and Evaluation) system. The cumulative effects of available data were processed for a meta-analysis using RevMan software. Eight RCTs with 177 participants were included. All studies were assessed as having some concerns regarding the risk of bias. rPMS significantly reduced pain intensity compared with the control, with a standardized mean difference (SMD) across visual analogue scales (VAS) and numerical rating scales (NRS) was -1.16 (95% CI: -1.56 to -0.76, I=21%, very low-quality evidence), indicating effective pain relief. For subgroup analysis of patients with chronic low back pain (CLBP), the meta-analysis revealed a remarkable pain relief (SMD=-0.92, 95% CI: -1.67 to -0.17, I=45%, very low-quality evidence). In addition, rPMS exhibited significant cumulative effects on disability improvement (Oswestry disability index: MD=-6.55, 95% CI: -10.27 to -2.82, I=0%, very low-quality evidence) but not on kinesiophobia (Tampa scale for kinesiophobia: MD=-1.81, 95% CI: -7.60 to 3.98, I=0%, low quality-evidence).
This meta-analysis demonstrated that rPMS is an effective method for relieving pain and improving disability in the treatment of CMP, especially for patients with CLBP.
重复经外周磁刺激（rPMS）是一种为临床康复治疗干预而开发的非侵入性无痛方法。慢性肌肉骨骼疼痛（CMP）起源于肌肉骨骼系统，会导致残疾和疼痛恐惧。它可能是CMP治疗的一种选择，但其有效性仍不明确。
于2023年5月26日根据严格的纳入和排除标准在PubMed、PEDro、Cochrane图书馆、科学网和Embase中检索相关文献。
使用Cochrane协作网的偏倚风险工具（ROB 2.0）和GRADE（推荐分级、评估、制定和评价）系统评估纳入研究的方法学质量。使用RevMan软件对可用数据的累积效应进行荟萃分析。纳入了八项随机对照试验，共177名参与者。所有研究在偏倚风险方面均被评估为存在一些问题。与对照组相比，rPMS显著降低了疼痛强度，视觉模拟量表（VAS）和数字评定量表（NRS）的标准化平均差（SMD）为-1.16（95%可信区间：-1.56至-0.76，I² = 21%，极低质量证据），表明有效缓解了疼痛。对于慢性下腰痛（CLBP）患者的亚组分析，荟萃分析显示疼痛得到显著缓解（SMD = -0.92，95%可信区间：-1.67至-0.17，I² = 45%，极低质量证据）。此外，rPMS对残疾改善有显著的累积效应（Oswestry残疾指数：MD = -6.55，95%可信区间：-10.27至-2.82，I² = 0%，极低质量证据），但对运动恐惧（坦帕运动恐惧量表：MD = -1.81，95%可信区间：-7.60至3.98，I² = 0%，低质量证据）没有影响。
这项荟萃分析表明，rPMS是治疗CMP时缓解疼痛和改善残疾的有效方法，尤其是对CLBP患者。
