Krylov S S
Ann Ist Super Sanita. 1978;14(1):77-80.
Pyrroxand and butyroxan -- original drugs possessing hyghly selective alpha-adreno-blocking action at peripheral and central level-relieve symptoms of abstinence syndrome caused by narcotics and other addicting drugs. On the basis of these data it is suggested that adrenergic structures of the brain play a key role in eliciting the abstinence syndrome.
吡罗昔坦和丁氧昔坦——最初具有外周和中枢高度选择性α-肾上腺素能阻断作用的药物——可缓解由麻醉品和其他成瘾药物引起的戒断综合征症状。基于这些数据,有人提出大脑中的肾上腺素能结构在引发戒断综合征中起关键作用。