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[Effect of psychotropic agents on the manifestation of the morphine abstinence syndrome in mice].

作者信息

Patkina N A, Evartau E E

出版信息

Farmakol Toksikol. 1980 Jan-Feb;43(1):19-23.

PMID:7189719
Abstract

Abstinence syndrome pattern produced by withdrawal of morphine injections in doses of 240 mg/kg daily was studied in experiments on mice. Pirroksan, butyroxan and carbidine (10 mg/kg intraperitoneally) inhibited manifestations of morphine withdrawal in an "open field" situation and depressed jumping activity. Phenazepam (20 mg/kg) depressed emotional hyperactivity in abstinent animals.

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