Sakamoto N, Yanagawa R, Ono E, Kida H, Mori M, Arimitsu Y, Akama K, Yasuda J, Too K
Zentralbl Bakteriol Mikrobiol Hyg A. 1985 Jul;259(4):548-56. doi: 10.1016/s0176-6724(85)80087-0.
Antibodies against leptospiral genus-specific antigen were detected in the sera from clinically diagnosed human leptospirosis and suspected animal leptospirosis by indirect hemagglutination (IHA) test with a partially purified genus-specific protein antigen (GP-Ag). The reaction was positive in the infected humans and animals irrespective of the leptospiral serovars. No significant correlation was found between IHA titer against GP-Ag and microscopic agglutination (MA) titer. IHA titer did not always develop in parallel with MA titers. Sera obtained from healthy individuals were negative in both IHA and MA tests.
