Mathad Ananth S, Varshney Surbhi, Usman Nawaz, Palod Akhil, Shetty Preethi S, Kumar Naveena An
Department of Surgical Oncology, Manipal Comprehensive Cancer Care Centre, Kasturba Medical College, Manipal, Manipal Academy of Higher Education,, Manipal, 576104 Karnataka India.
Indian J Otolaryngol Head Neck Surg. 2025 Jul;77(7):2591-2595. doi: 10.1007/s12070-025-05580-8. Epub 2025 May 23.
Tracheal invasion by thyroid cancers poses significant surgical challenges. In this case series, we present our experience of tracheal resection and reconstruction in eight patients. This study highlights the importance of a coordinated multidisciplinary approach and technique of partial tracheal resection as well as evaluates the outcomes of this complex surgical intervention.
This study is the retrospective analysis of prospectively maintained data base of Thyroid cancer.
The tracheal resection and reconstruction was performed in eight patients, including five males and three females, with a median age of 51 years. Seven patients had papillary thyroid carcinoma, while one had medullary thyroid carcinoma. Seven underwent partial tracheal resection, and one had full-thickness resection with anastomosis, achieving negative margins in all cases. No major complications related to tracheal resection and reconstruction except one patient had mortality due to carotid blow out. Over a median follow-up of 24 months (12-28 months), 6 patients remained disease-free.
Tracheal resection and reconstruction for thyroid cancer with tracheal invasion is a viable approach, offering favourable outcomes in carefully selected patients. While the procedure is associated with inherent risks, a multidisciplinary approach and technical expertise are pivotal in minimizing complications and optimizing survival.
甲状腺癌侵犯气管给手术带来了重大挑战。在本病例系列中,我们介绍了8例患者气管切除及重建的经验。本研究强调了多学科协作方法及部分气管切除技术的重要性,并评估了这种复杂手术干预的结果。
本研究是对前瞻性维护的甲状腺癌数据库进行的回顾性分析。
8例患者接受了气管切除及重建,其中男性5例,女性3例,中位年龄51岁。7例为甲状腺乳头状癌,1例为甲状腺髓样癌。7例行部分气管切除,1例行全层切除并吻合,所有病例切缘均阴性。除1例患者因颈动脉破裂死亡外,无与气管切除及重建相关的严重并发症。中位随访24个月(12 - 28个月),6例患者无疾病复发。
对于侵犯气管的甲状腺癌,气管切除及重建是一种可行的方法,在精心挑选的患者中可获得良好结果。虽然该手术存在固有风险,但多学科方法和技术专长对于减少并发症及优化生存至关重要。