Verdaguer-Figuerola Arnau, Andriola Vito, Soler-Cano Albert, Alavedra-Massana Anna, Carballo Alejandro, Tey-Pons Marc
Medical Resident of the Orthopaedic and Trauma, Department, Parc Taulí Hospital Universitari, Institut d'Investigació i Innovació Parc Taulí (I3PT-CERCA), Universitat Autònoma de Barcelona, Sabadell, Spain.
Surgeon of Orthopaedic and Trauma Department, Parc Taulí, Hospital Universitari, Institut d'Investigació i Innovació Parc Taulí (I3PT-CERCA), Universitat Autònoma de Barcelona, Sabadell, Spain.
Arthroplast Today. 2025 May 26;33:101692. doi: 10.1016/j.artd.2025.101692. eCollection 2025 Jun.
Total hip arthroplasty (THA) is a cost-effective solution for osteoarthritis, but it is often associated with postoperative pain that hinders early mobilization and rehabilitation. Local infiltration analgesia (LIA) has emerged as a potential strategy to reduce pain and speed recovery in THA patients. However, the efficacy of LIA in THA remains controversial, with conflicting evidence regarding its impact on pain management, length of hospital stays, and other outcomes. The aim of this study was to evaluate the efficacy of LIA in pain management after THA.
A blinded randomized controlled trial was conducted in 108 patients undergoing THA at a single center. Patients were randomized to receive either LIA or non-LIA during surgery according to an accepted protocol. Surgical procedures were standardized, and outcomes including pain, blood loss, length of hospital stay, functional outcomes, and patient satisfaction were assessed.
No significant differences were observed between the LIA group and the control group in pain scores at 24 and 48 hours postoperatively, blood loss, length of hospital stay, or functional outcomes at 3 and 6 months. Patient satisfaction was similar between groups. There were no major complications.
The use of LIA did not improve pain management, hospital stay, blood loss, functional outcomes at 3 and 6 months postoperatively or patient satisfaction at 3 and 12 months after primary THA.
全髋关节置换术（THA）是治疗骨关节炎的一种经济有效的方法，但术后疼痛常与之相关，这会妨碍早期活动和康复。局部浸润镇痛（LIA）已成为减轻THA患者疼痛并加速恢复的一种潜在策略。然而，LIA在THA中的疗效仍存在争议，关于其对疼痛管理、住院时间及其他结局的影响，证据相互矛盾。本研究的目的是评估LIA在THA术后疼痛管理中的疗效。
在一个中心对108例行THA的患者进行了一项双盲随机对照试验。根据既定方案，患者在手术期间被随机分配接受LIA或非LIA。手术操作标准化，并评估包括疼痛、失血、住院时间、功能结局和患者满意度等结局。
LIA组和对照组在术后24小时和48小时的疼痛评分、失血量、住院时间，或3个月和6个月时的功能结局方面均未观察到显著差异。两组患者的满意度相似。未出现重大并发症。
在初次THA术后3个月和6个月时，使用LIA并未改善疼痛管理、住院时间、失血量、功能结局，或术后3个月和12个月时的患者满意度。
