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3D打印在上肢疾病定制治疗中的应用。

Application of 3D printing for customised treatment of upper limb disorders.

作者信息

Gupta Saurabh Kumar, Holla Navaneeth, Suwas Satyam, Chatterjee Kaushik, Vamsi Krishna Sathya

机构信息

Department of Materials Engineering, Indian Institute of Science, C.V. Raman Avenue, Bangalore, 560012, India.

Department of Hand Surgery, Sanjay Gandhi Institute of Orthopaedics and Trauma, Byrasandra, Jayanagar, Bangalore, 560011, India.

出版信息

J Hand Microsurg. 2025 May 19;17(4):100284. doi: 10.1016/j.jham.2025.100284. eCollection 2025 Jul.

Abstract

PURPOSE

Three-dimensional (3D) technology is rapidly emerging as a valuable tool in the medical and healthcare industry, particularly for performing corrective osteotomies in upper limb extremities. This study involved patients with impaired upper limb function who underwent corrective osteotomies using a computer-assisted 3D surgical planning process with 3D-printed, patient-specific plates. The biomechanical performance of these 3D-printed, patient-specific plates was enhanced while maintaining crucial properties such as corrosion resistance and biocompatibility, ensuring their safety for clinical application in humans. The surgical outcomes were analyzed by visualizing bone healing, and an evaluation was conducted to assess the success of these methodologies by comparing the clinical outcomes achieved with those planned during the surgical planning phase.

PATIENTS AND METHODS

Eight cases involving malunions and deformities were treated using patient-specific bone plates fabricated through metal additive manufacturing. Preoperative computed tomography (CT) scans were used to generate virtual bone models for surgical planning. Normal/anatomical bone alignment was achieved by mirroring the contralateral healthy bone and projecting it onto the affective bone model. Surgical guides and patient-specific bone implants were then designed. These implants underwent an innovative cyclic heat treatment to optimize their strength and ductility for enhanced biomechanical performance.

RESULTS

The final outcomes for the patients were assessed using functional scoring and radiographs. The 3D-printed surgical guides facilitated accurate osteotomy angulation and precise positioning of drilled holes, ensuring optimal placement of customised, mechanically enhanced bone plates. All patients demonstrated improved DASH scores and experienced reduced or no pain after healing.

CONCLUSIONS

This study demonstrates the success of personalized treatment for upper limb disorders using 3D-printed, patient-specific plates, which showed improved biomechanical performance after tailored heat treatment. This method of preparing patient-specific implants offers a safe and highly effective approach to treating malunions and deformities in the upper limbs with reduced surgical time.

摘要

目的

三维(3D)技术正迅速成为医疗保健行业中的一种重要工具,尤其是在上肢进行矫正截骨手术方面。本研究纳入了上肢功能受损且使用计算机辅助3D手术规划流程及3D打印的个性化钢板进行矫正截骨手术的患者。这些3D打印的个性化钢板在保持耐腐蚀性和生物相容性等关键特性的同时,其生物力学性能得到了增强,确保了它们在人体临床应用中的安全性。通过可视化骨愈合情况分析手术结果,并通过比较手术规划阶段计划的临床结果与实际取得的临床结果来评估这些方法的成功率。

患者与方法

八例涉及骨不连和畸形的病例采用通过金属增材制造制作的个性化骨板进行治疗。术前计算机断层扫描(CT)用于生成用于手术规划的虚拟骨模型。通过镜像对侧健康骨并将其投影到患侧骨模型上实现正常/解剖学骨对线。然后设计手术导板和个性化骨植入物。这些植入物经过创新的循环热处理,以优化其强度和延展性,增强生物力学性能。

结果

使用功能评分和X线片评估患者的最终结果。3D打印的手术导板有助于准确的截骨角度和钻孔的精确定位,确保定制的、机械性能增强的骨板的最佳放置。所有患者的DASH评分均有所改善,愈合后疼痛减轻或消失。

结论

本研究证明了使用3D打印的个性化钢板对上肢疾病进行个性化治疗的成功,这些钢板在经过定制热处理后生物力学性能得到改善。这种制备个性化植入物的方法为治疗上肢骨不连和畸形提供了一种安全、高效的方法,且手术时间缩短。

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