Prevalence and Independent Risk Factors of Anxiety and Depression Symptoms in Glioma Patients: A Cross-Sectional Analysis.

BACKGROUND

To investigate the current status of anxiety and depression symptoms in patients with brain glioma and identify the risk factors associated with anxiety and depression symptoms.

METHODS

A total of 105 patients diagnosed with glioma at Longgang Central Hospital of Shenzhen from January 2021 to April 2024 were included in this study. The Hospital Anxiety and Depression Scale (HADS) was used to assess the anxiety and depression symptoms of the patients, who were then grouped based on their scores. Chi-square tests and binary logistic regression analyses were performed to identify the independent risk factors for anxiety and depression symptoms in glioma patients.

RESULTS

The average HADS-Anxiety score among glioma patients was 8.72 ± 3.41, with an anxiety symptoms prevalence of 61.90% (65/105). The average HADS-Depression score was 7.73 ± 2.91, with a depression symptoms prevalence of 55.24% (58/105). Among them, 58 patients (55.24%) had both anxiety and depression symptoms, seven patients (6.67%) had only anxiety symptoms, and 40 patients (38.10%) had neither anxiety nor depression. The results of binary tic regression analysis showed that family monthly income, seizures, sleep quality, and cognitive function impairment were independent risk factors for anxiety and depression symptoms ( < .05). Marital status was an independent risk factor for depression symptoms ( < .05).

CONCLUSION

Glioma patients exhibit a high incidence of anxiety and depression symptoms. The occurrence of these conditions is significantly associated with lower monthly household income, seizure occurrence, sleep disturbances, and cognitive impairment.