Rothendler J A, Boucher C A, Strauss H W, Pohost G M, Okada R D
Am Heart J. 1985 Oct;110(4):830-5. doi: 10.1016/0002-8703(85)90465-x.
Post-exercise elevation of the lung/myocardial thallium ratio and a high lung clearance rate between initial and delayed images have been reported to be markers for exercise-induced left ventricular (LV) dysfunction associated with coronary artery disease (CAD). We performed thallium exercise tests on 60 patients, 42 with CAD, in order to determine the effect of delaying initial imaging on detection of elevated lung thallium. In addition to images obtained at 2 minutes and at 2 hours after exercise, 18-minute images were also obtained to simulate such a delay. Because of rapid isotope clearance in those with initially elevated lung activity, there was decreased sensitivity of both the initial lung/myocardial ratio and lung thallium clearance for detecting CAD, using the 18-minute image as the initial post exercise study. We conclude that initial imaging should be done in the anterior view early after exercise to optimize detection of elevated lung thallium.
运动后肺/心肌铊摄取率升高以及初始图像与延迟图像之间的高肺清除率，已被报道为与冠状动脉疾病（CAD）相关的运动诱发左心室（LV）功能障碍的标志物。我们对60例患者（42例患有CAD）进行了铊运动试验，以确定延迟初始成像对检测肺铊摄取升高的影响。除了在运动后2分钟和2小时获得的图像外，还获取了18分钟的图像以模拟这种延迟。由于初始肺活性升高者的同位素清除迅速，以18分钟图像作为运动后的初始研究时，初始肺/心肌比值和肺铊清除率检测CAD的敏感性均降低。我们得出结论，运动后应尽早在前位进行初始成像，以优化对肺铊摄取升高的检测。
