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大学心脏病专家如何治疗室性早搏:对65家大学医学中心的全国性调查。

How the university cardiologist treats ventricular premature beats: a nationwide survey of 65 University Medical Centers.

作者信息

Vlay S C

出版信息

Am Heart J. 1985 Oct;110(4):904-12. doi: 10.1016/0002-8703(85)90485-5.

DOI:10.1016/0002-8703(85)90485-5
PMID:4050669
Abstract

Sixty-five of 118 university cardiologists responded to a survey of indications for treatment of ventricular ectopy, particularly in the completely asymptomatic patient or those with palpitations as the only symptom. The percentage of cardiologists treating these patients increased as the complexity of ventricular ectopy increased, as the severity of underlying heart disease increased, as the symptoms increased from completely asymptomatic to palpitations or skipped beats, if the patient experienced dizziness or syncope, and if the patient had complex VPBs or asymptomatic VT after MI. Ninety-eight percent of respondents had patients who experienced exacerbation of arrhythmia with antiarrhythmic drugs. Of the conventional type 1 drugs, the drug of first choice was quinidine for 60%, procainamide for 37%, and disopyramide for 3%. The accepted indications for electrophysiologic testing included survivors of sudden cardiac arrest and patients with symptomatic VT.

摘要

118名大学心脏病专家中有65人回复了一项关于室性异位心律治疗指征的调查,特别是针对完全无症状的患者或仅有心悸这一症状的患者。随着室性异位心律复杂性的增加、潜在心脏病严重程度的增加、症状从完全无症状发展为心悸或漏跳、患者出现头晕或晕厥,以及患者在心肌梗死后出现复杂性室性早搏或无症状室性心动过速,治疗这些患者的心脏病专家比例也随之增加。98%的受访者有患者在使用抗心律失常药物后出现心律失常加重的情况。在传统的1类药物中,60%的人首选奎尼丁,37%的人首选普鲁卡因胺,3%的人首选丙吡胺。电生理检查的公认指征包括心脏骤停幸存者和有症状的室性心动过速患者。

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Am Heart J. 1985 Oct;110(4):904-12. doi: 10.1016/0002-8703(85)90485-5.
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Prescribing trends and pharmacoeconomic considerations in the treatment of arrhythmias. Focus on atrial fibrillation and flutter.心律失常治疗中的处方趋势及药物经济学考量。重点关注心房颤动和心房扑动。
Pharmacoeconomics. 1995 Jun;7(6):521-33. doi: 10.2165/00019053-199507060-00006.
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Therapeutic drug monitoring of antiarrhythmic drugs. Rationale and current status.
抗心律失常药物的治疗药物监测。基本原理与现状。
Clin Pharmacokinet. 1990 Feb;18(2):91-103. doi: 10.2165/00003088-199018020-00001.
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Practical optimisation of antiarrhythmic drug therapy using pharmacokinetic principles.运用药代动力学原理对抗心律失常药物治疗进行实际优化。
Clin Pharmacokinet. 1991 Feb;20(2):151-66. doi: 10.2165/00003088-199120020-00006.
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Selection bias in using data from one population to another: common pitfalls in the interpretation of medical literature.将一个人群的数据应用于另一个人群时的选择偏倚:医学文献解读中的常见陷阱。
Theor Med. 1992 Sep;13(3):255-9. doi: 10.1007/BF00489202.