Froom P, Froom J
Kibbutz Maagan Michael, DN Manashe, Israel.
Theor Med. 1992 Sep;13(3):255-9. doi: 10.1007/BF00489202.
The prevalence, course and prognosis of diseases in patients referred to tertiary medical centers frequently differ from those treated in primary care settings. Extrapolation of findings from one population to another may therefore be unwarranted. Other factors that contribute to misinterpretation of medical literature include failure to distinguish statistical from clinical significance and advocacy of medical interventions prior to adequate clinical trials.
转诊至三级医疗中心的患者所患疾病的患病率、病程和预后通常与在初级保健机构接受治疗的患者不同。因此，将一个人群的研究结果推断至另一人群可能是不合理的。导致医学文献解读错误的其他因素包括未能区分统计学意义和临床意义，以及在充分的临床试验之前就鼓吹医疗干预措施。
