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纤维肌痛中的疼痛、愤怒和沉思:恶性循环?

Pain, Anger, and Rumination in Fibromyalgia: A Vicious Cycle?

作者信息

Tenti Michael, Varallo Giorgia, Cilenti Federica, Raffaeli William, Scorza Maristella, Rubichi Sandro, Pietrabissa Giada, Castelnuovo Gianluca, Gremigni Paola, Casu Giulia

机构信息

ISAL Foundation, Institute for Research on Pain, 47921 Rimini, Italy.

Studi Cognitivi, Cognitive Psychotherapy School and Research Center, 20121 Milan, Italy.

出版信息

J Clin Med. 2025 May 23;14(11):3662. doi: 10.3390/jcm14113662.

Abstract

Fibromyalgia is a debilitating syndrome characterized by persistent pain. Emerging evidence highlights the role of emotional and cognitive processes in modulating pain experience. Anger, for example, can influence pain and patients' adjustment to the disease. Studies showed that metacognitions and anger rumination can worsen state anger, thereby increasing perceived pain intensity. The present study aims to investigate the presence of a relationship between pain, dysfunctional metacognitions, anger rumination, and state anger. The study included 446 participants who self-reported having a diagnosis of fibromyalgia confirmed by a rheumatologist or pain specialist. Participants completed self-report measures of metacognitions, anger rumination, state anger, and pain intensity. The serial mediation analysis was performed using Hayes' PROCESS macro (Model 6). Pain intensity showed a significant positive effect on negative beliefs about worry (β = 0.09; < 0.05), need to control thoughts (β = 0.09; < 0.05), and cognitive self-consciousness (β = 0.12; < 0.05), but not on anger rumination. Across all serial mediation models, the direct effect of pain intensity on state anger remained significant even after controlling for the effect of mediators, indicating partial mediation. This study suggests a vicious cycle involving dysfunctional metacognitions, anger rumination, state anger, and pain intensity. Our findings also indicate a potential influence of pain on metacognitions and suggest a direct association between pain intensity and state anger. Interventions for anger management in fibromyalgia should consider dysfunctional metacognitions and anger rumination.

摘要

纤维肌痛是一种以持续性疼痛为特征的使人衰弱的综合征。新出现的证据凸显了情绪和认知过程在调节疼痛体验中的作用。例如,愤怒会影响疼痛以及患者对疾病的适应。研究表明,元认知和愤怒反刍会加剧状态性愤怒,从而增加感知到的疼痛强度。本研究旨在调查疼痛、功能失调的元认知、愤怒反刍和状态性愤怒之间是否存在关联。该研究纳入了446名参与者,他们自我报告经风湿病学家或疼痛专家确诊患有纤维肌痛。参与者完成了关于元认知、愤怒反刍、状态性愤怒和疼痛强度的自我报告测量。使用海斯的PROCESS宏程序(模型6)进行了系列中介分析。疼痛强度对关于担忧的消极信念(β = 0.09;<0.05)、控制思维的需求(β = 0.09;<0.05)和认知自我意识(β = 0.12;<0.05)有显著的正向影响,但对愤怒反刍没有影响。在所有系列中介模型中,即使在控制了中介变量的影响后,疼痛强度对状态性愤怒的直接效应仍然显著,表明存在部分中介作用。本研究表明存在一个涉及功能失调的元认知、愤怒反刍、状态性愤怒和疼痛强度的恶性循环。我们的研究结果还表明疼痛对元认知有潜在影响,并表明疼痛强度与状态性愤怒之间存在直接关联。纤维肌痛患者的愤怒管理干预措施应考虑功能失调的元认知和愤怒反刍。

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