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纤维肌痛、类风湿关节炎、脊柱关节炎和干燥综合征的比较研究;疾病对生活质量、心理调整和应对策略使用的影响。

A Comparative Study of Fibromyalgia, Rheumatoid Arthritis, Spondyloarthritis, and Sjögren's Syndrome; Impact of the Disease on Quality of Life, Psychological Adjustment, and Use of Coping Strategies.

机构信息

Département de Psychologie, Université de Tours, EE 1901 Qualipsy 'Qualité de Vie et Santé Psychologique,' Tours Cedex, France.

Service de Rhumatologie, CHRU de Tours, Université de Tours, Tours, France.

出版信息

Pain Med. 2021 Feb 23;22(2):372-381. doi: 10.1093/pm/pnz255.

Abstract

BACKGROUND

Fibromyalgia, rheumatoid arthritis, spondyloarthritis, and Sjögren's syndrome are chronic rheumatic diseases with very different clinical characteristics, but which share symptoms such as pain and fatigue. The aim of the study was to examine the impact of the disease on psychological adaptation in fibromyalgia compared with other rheumatic diseases (rheumatoid arthritis, spondyloarthritis, and Sjögren's syndrome).

METHODS

In a multicenter study, 165 women with rheumatic diseases (48 with fibromyalgia, 47 with rheumatoid arthritis, 47 with spondyloarthritis, 23 with Sjögren's syndrome) completed the General Health Questionnaire-28 (emotional distress), Fatigue Severity Scale (fatigue), Fibromyalgia Impact Questionnaire (impact of the disease), Coping Strategies Questionnaire (coping), and Mini International Neuropsychiatric Interview (comorbidity with DSM IV axis-I disorders). We used the Kruskal-Wallis test, Mann-Whitney U test, and chi2 test to compare comorbid anxiety and depressive disorders and to compare the impact of the disease on patients' mental well-being and daily life and adjustment (coping strategies).

RESULTS

Anxiety and depressive disorders were more common in fibromyalgia patients; they had higher scores on impact of the disease, physical symptoms, pain, and fatigue than rheumatoid arthritis patients and reported more fatigue than patients with spondyloarthritis. Overall, they used more maladaptive coping strategies (less use of distancing from pain than patients with rheumatoid arthritis and spondyloarthritis, less use of ignoring pain sensations, and more use of catastrophizing than those with rheumatoid arthritis). No differences were found between fibromyalgia and Sjögren's syndrome on impact and adjustment.

CONCLUSIONS

Compared with other rheumatic diseases, fibromyalgia has a greater impact on daily life; patients have more difficulty adjusting to the disease and generally use poorer strategies to cope with pain.

摘要

背景

纤维肌痛、类风湿关节炎、脊柱关节炎和干燥综合征是具有非常不同临床特征的慢性风湿性疾病,但它们都有疼痛和疲劳等共同症状。本研究旨在检查与其他风湿性疾病(类风湿关节炎、脊柱关节炎和干燥综合征)相比,纤维肌痛对心理适应的影响。

方法

在一项多中心研究中,165 名患有风湿性疾病的女性(48 名纤维肌痛患者、47 名类风湿关节炎患者、47 名脊柱关节炎患者、23 名干燥综合征患者)完成了一般健康问卷-28(情绪困扰)、疲劳严重程度量表(疲劳)、纤维肌痛影响问卷(疾病影响)、应对策略问卷(应对)和迷你国际神经精神访谈(与 DSM-IV 轴-I 障碍共病)。我们使用 Kruskal-Wallis 检验、Mann-Whitney U 检验和卡方检验比较共病焦虑和抑郁障碍,并比较疾病对患者心理健康和日常生活以及调整(应对策略)的影响。

结果

纤维肌痛患者更常见焦虑和抑郁障碍;他们在疾病影响、身体症状、疼痛和疲劳方面的得分高于类风湿关节炎患者,且比脊柱关节炎患者报告的疲劳更严重。总体而言,他们使用的应对策略适应性更差(与类风湿关节炎和脊柱关节炎患者相比,对疼痛的回避程度较低,对疼痛感觉的忽视程度较高,而对灾难化的程度较高)。纤维肌痛与干燥综合征在疾病影响和调整方面无差异。

结论

与其他风湿性疾病相比,纤维肌痛对日常生活的影响更大;患者更难以适应疾病,且通常使用较差的策略来应对疼痛。

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