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长期低剂量糖皮质激素治疗与干燥综合征中明显肾小管酸中毒的缓解相关。

Long-term low-dose glucocorticoid therapy associated with remission of overt renal tubular acidosis in Sjögren's syndrome.

作者信息

el-Mallakh R S, Bryan R K, Masi A T, Kelly C E, Rakowski K J

出版信息

Am J Med. 1985 Oct;79(4):509-14. doi: 10.1016/0002-9343(85)90040-3.

DOI:10.1016/0002-9343(85)90040-3
PMID:4050835
Abstract

Renal tubular acidosis and focal interstitial inflammatory cell infiltrate secondary to Sjögren's syndrome remitted with low-dose glucocorticoid therapy over five and one half years in a patient with associated mild systemic lupus erythematosus. Such response has not been previously documented. This observation may have therapeutic applications for renal tubular acidosis associated with Sjögren's syndrome that deserve further investigation.

摘要

一名伴有轻度系统性红斑狼疮的患者,其继发于干燥综合征的肾小管酸中毒和局灶性间质炎性细胞浸润,在接受低剂量糖皮质激素治疗五年半后得到缓解。此前尚未有过这种反应的记录。这一观察结果可能对与干燥综合征相关的肾小管酸中毒具有治疗应用价值,值得进一步研究。

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Long-term low-dose glucocorticoid therapy associated with remission of overt renal tubular acidosis in Sjögren's syndrome.长期低剂量糖皮质激素治疗与干燥综合征中明显肾小管酸中毒的缓解相关。
Am J Med. 1985 Oct;79(4):509-14. doi: 10.1016/0002-9343(85)90040-3.
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Renal tubular dysfunction in primary Sjögren's syndrome: clinical studies in 27 patients.原发性干燥综合征的肾小管功能障碍:27例患者的临床研究
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