Hu Zhe-Hao, Zhang Xin-Yue, Jiang Hong-Zhan, Li Xue-Jing, Hao Yu-Fang
School of Nursing, Beijing University of Chinese Medicine, Beijing 100029, China.
School of Traditional Chinese Medicine, Beijing University of Chinese Medicine, Beijing 100029, China.
Healthcare (Basel). 2025 May 30;13(11):1301. doi: 10.3390/healthcare13111301.
: Motor Function Disorders (MFDs) are common conditions in children with cerebral palsy and closely related to muscle spasticity. Catgut Embedment in Acupoint (CEA) has shown promise as an important adjunctive therapy but current evidence remains insufficient. The aim of this study was to evaluate the efficacy and safety of CEA in Pediatric-Cerebral-Palsy Motor Function Disorders (PCPMFDs). : PubMed, Cochrane Library, Embase, Web of Science, four Chinese databases and two clinical trial registries were searched to include randomized controlled trials of patients with PCPMFDs treated with CEA combined with conventional rehabilitation. Meta-analysis was performed using Review Manager 5.4, Stata 18 and R Studio software 2025, and risk of bias was assessed for the included studies using the Cochrane Collaboration Network tool. : A total of 17 papers were included, including 1106 PCPMFDs patients with a wide range of conditions, age ≤ 9 years, and rehabilitation training mostly using Bobath/Vojta therapy. Meta-analysis showed that CEA was effective in improving MFDs with the Gross Motor Function Measure Scale (SMD, 0.90 [95% CI, 0.57 to 1.23], < 0.0001) and the modified Ashworth Scale (MD, -0.40 [95% CI, -0.58 to -0.23], < 0.0001). Preliminary results suggested that a treatment regimen, which consisted of three monthly sessions and lasted for one to two months, was most effective. : CEA is an effective complementary treatment for patients with PCPMFDs with mild adverse effects. However, due to the relatively new perspective of this study, only a small number of researchers have focused on this area and conducted studies, resulting in fewer included studies meeting requirements, which is a direct result of the fact that this study, although informative, still requires a significant amount of research before clear evidence-based recommendations can be developed.
运动功能障碍（MFDs）是脑瘫患儿的常见病症，与肌肉痉挛密切相关。穴位埋线（CEA）已显示出作为一种重要辅助治疗方法的前景，但目前证据仍不充分。本研究旨在评估穴位埋线治疗小儿脑瘫运动功能障碍（PCPMFDs）的疗效和安全性。检索了PubMed、Cochrane图书馆、Embase、Web of Science、四个中文数据库和两个临床试验注册库，以纳入接受穴位埋线联合传统康复治疗的PCPMFDs患者的随机对照试验。使用Review Manager 5.4、Stata 18和R Studio软件2025进行荟萃分析，并使用Cochrane协作网络工具评估纳入研究的偏倚风险。共纳入17篇论文，包括1106例PCPMFDs患者，病情范围广泛，年龄≤9岁，康复训练大多采用Bobath/Vojta疗法。荟萃分析表明，穴位埋线在改善运动功能障碍方面有效，采用粗大运动功能测量量表（标准化均数差，0.90 [95%可信区间，0.57至1.23]，P<0.0001）和改良Ashworth量表（平均差，-0.40 [95%可信区间，-0.58至-0.23]，P<0.0001）评估。初步结果表明，每月进行三次、持续一至两个月的治疗方案最为有效。穴位埋线是治疗PCPMFDs患者的一种有效补充治疗方法，不良反应轻微。然而，由于本研究视角相对较新，只有少数研究人员关注该领域并开展研究，导致符合要求的纳入研究较少，这直接导致本研究虽然提供了信息，但在能够制定明确的循证建议之前仍需要大量研究。
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