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酸奶与灭活疫苗联合调节猫的脂质代谢、抗炎及粪便微生物群。

Yogurt in Combination with Inactivated Modulated Feline Lipid Metabolism, Anti-Inflammation and Fecal Microbiota.

作者信息

Sun Jintao, Gu Xinshu, Wang Jiaxue, Wang Xiumin, Wang Zhenlong, Tao Hui, Wang Jinquan, Han Bing

机构信息

Key Laboratory of Feed Biotechnology of Ministry of Agriculture and Rural Affairs, Institute of Feed Research, Chinese Academy of Agricultural Sciences, No. 12 Zhong Guan Cun South Street, Haidian District, Beijing 100081, China.

College of Animal Science and Technology, Jiangxi Agricultural University, No. 1225, Zhimin Avenue, Xinjian District, Nanchang 330045, China.

出版信息

Animals (Basel). 2025 May 23;15(11):1531. doi: 10.3390/ani15111531.

Abstract

Yogurt and postbiotics are both beneficial for intestinal health of pets. This study was conducted to investigate the effects of yogurt with postbiotics in cats. A total of 18 adult cats were randomly divided into three groups, CK group (Control = 6, free feeding and drinking without any probiotic products), Y group (Yogurt, = 6, 50 g/day), and YP group (Yogurt + 2% postbiotics, 50 g/day), with the same environment and diet. On the 21st day, blood and fecal samples were collected and tested for biochemical indices, immunological parameters, inflammatory factors, and fecal flora, respectively. The results showed that feeding postbiotic yogurt to cats significantly reduced the levels of total bilirubin (TBIL), total bile acids (TBA), triglycerides (TG), glucose (GLU), urea nitrogen (BUN), creatinine (CREA), tumor necrosis factor-alpha (TNF-α), and Interleukin-6 (IL-6) ( < 0.05), and significantly increased Immunoglobulin A (sIgA) ( < 0.05) compared to the CK group. The abundance of in YP group was elevated, the Shannon violin plots showed that the intestinal flora of the YP group was less dispersed. Notably and were significantly elevated in the Y group ( < 0.05) and subsp. in the YP group ( < 0.05). Therefore, this study suggests that yogurt with postbiotic is a good choice for improving intestinal health and immune function in cats and possesses good research and application prospects.

摘要

酸奶和后生元均对宠物肠道健康有益。本研究旨在调查添加后生元的酸奶对猫的影响。总共18只成年猫被随机分为三组,CK组(对照组=6只,自由进食和饮水,不使用任何益生菌产品),Y组(酸奶组,=6只,50克/天),YP组(酸奶+2%后生元组,50克/天),所有组处于相同环境并采用相同饮食。在第21天,分别采集血液和粪便样本,检测生化指标、免疫参数、炎症因子和粪便菌群。结果表明,与CK组相比,给猫喂食含后生元的酸奶显著降低了总胆红素(TBIL)、总胆汁酸(TBA)、甘油三酯(TG)、葡萄糖(GLU)、尿素氮(BUN)、肌酐(CREA)、肿瘤坏死因子-α(TNF-α)和白细胞介素-6(IL-6)的水平(<0.05),并显著提高了免疫球蛋白A(sIgA)(<0.05)。YP组中[此处原文缺失具体菌群名称]的丰度升高,香农小提琴图显示YP组的肠道菌群分布较不分散。值得注意的是,Y组中[此处原文缺失具体菌群名称]和[此处原文缺失具体菌群名称]显著升高(<0.05),YP组中[此处原文缺失具体菌群名称]亚种显著升高(<0.05)。因此

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