Waldrop T G, Mitchell J H
Am J Physiol. 1985 Oct;249(4 Pt 2):H710-4. doi: 10.1152/ajpheart.1985.249.4.H710.
The purpose of this study was to measure blood flow to various tissues during static muscular contraction in anesthetized cats and to evaluate if the baroreflex modulates the cardiovascular responses to muscular contraction. Contraction of the hindlimb muscles induced by ventral root stimulation caused increases in arterial pressure (delta 37.8 +/- 5.5 mmHg) and heart rate (delta 13.9 +/- 3.1 beats/min). Increases in blood flow to the heart, working skeletal muscles, and selected areas of the central nervous system occurred during muscular contraction. Blood flow to visceral organs did not change during muscular contraction. Baroreceptor-denervated cats showed a greater rise in arterial pressure (delta 55.5 +/- 5.5 mmHg) during muscular contraction than did the baroreceptor-intact cats. However, blood flow responses were similar in both groups. Thus the baroreceptor reflex modulates the pressor response without changing the alteration in blood flow during induced muscular contraction in anesthetized cats.
本研究的目的是测量麻醉猫在静态肌肉收缩期间流向各种组织的血流量，并评估压力感受器反射是否调节对肌肉收缩的心血管反应。由腹根刺激引起的后肢肌肉收缩导致动脉压升高（37.8±5.5 mmHg）和心率加快（13.9±3.1次/分钟）。在肌肉收缩期间，流向心脏、工作的骨骼肌和中枢神经系统选定区域的血流量增加。肌肉收缩期间内脏器官的血流量没有变化。压力感受器去神经支配的猫在肌肉收缩期间动脉压的升高（55.5±5. mmHg）比压力感受器完整的猫更大。然而，两组的血流反应相似。因此，在麻醉猫的诱发肌肉收缩过程中，压力感受器反射调节升压反应，而不改变血流变化。
