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猫的压力感受器反射以及与持续肌肉收缩相关的心血管变化。

The baroreceptor reflex and the cardiovascular changes associated with sustained muscular contraction in the cat.

作者信息

Coote J H, Dodds W N

出版信息

Pflugers Arch. 1976 May 12;363(2):167-73. doi: 10.1007/BF01062286.

DOI:10.1007/BF01062286
PMID:945551
Abstract

In decerebrate unanaesthetised cats the cardiovascular effects of raising the pressure in a blind sac preparation of a carotid sinus on one side were examined at rest and during sustained contractions of hind-limb muscles. During a tetanic contraction the absolute value of the blood pressure and heart-rate components of the baroreceptor reflex response were not significantly changed from those at rest. The curve relating heart-rate and mean blood pressure, during carotid sinus distension, was similar at rest and when the muscles of the hind-limb were contracting tetanically, although each value of heart-rate was greater, suggesting a resetting of the baroreceptor reflex. By contrast, in the same experiments, suppression of the baroreceptor reflex changes in heart-rate and blood pressure could be demonstrated during the increases of blood pressure and heart-rate elicited by the afferent discharge from muscles during sustained contraction are buffered to some extent by the baroreceptors, though their inhibitoru effect is incomplete under these conditions.

摘要

在去大脑未麻醉的猫身上,研究了在一侧颈动脉窦盲囊制备物中升高压力时,在静息状态和后肢肌肉持续收缩期间的心血管效应。在强直收缩期间,压力感受器反射反应的血压和心率成分的绝对值与静息时相比无显著变化。在静息时以及后肢肌肉进行强直收缩时,颈动脉窦扩张期间心率与平均血压的关系曲线相似,尽管每个心率值都更高,这表明压力感受器反射发生了重置。相比之下,在相同实验中,在持续收缩期间肌肉传入放电引起的血压和心率升高过程中,可以证明压力感受器反射对心率和血压变化的抑制作用,尽管在这些条件下其抑制作用不完全,但压力感受器在一定程度上缓冲了这种变化。

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