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2
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J Occup Med. 1984 Aug;26(8):571-4.
3
Polycyclic aromatic hydrocarbons in the occupational environment: with special reference to benzo[a]pyrene measurements in Swedish industry.职业环境中的多环芳烃:特别提及瑞典工业中苯并[a]芘的测量
Scand J Work Environ Health. 1982 Mar;8(1):1-19. doi: 10.5271/sjweh.2503.
4
Analysis of relative survival and proportional mortality.相对生存率和比例死亡率分析。
Comput Biomed Res. 1974 Aug;7(4):325-32. doi: 10.1016/0010-4809(74)90010-x.
5
Inhalation of benzpyrene and cancer in man.人体吸入苯并芘与癌症
Ann N Y Acad Sci. 1976;271:116-24. doi: 10.1111/j.1749-6632.1976.tb23100.x.
6
Carcinogenic potential of petroleum hydrocarbons: a critical review of the literature.石油烃的致癌潜力:文献综述
J Environ Pathol Toxicol. 1979 Dec;3(1-2):483-563.

接触煤焦油沥青挥发物和焊接排放物的工人死亡率:一项流行病学筛选工作。

Mortality among workers exposed to coal tar pitch volatiles and welding emissions: an exercise in epidemiologic triage.

作者信息

Silverstein M, Maizlish N, Park R, Mirer F

出版信息

Am J Public Health. 1985 Nov;75(11):1283-7. doi: 10.2105/ajph.75.11.1283.

DOI:10.2105/ajph.75.11.1283
PMID:4051064
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1646700/
Abstract

The United Automobile Workers International Union has established a system of epidemiologic triage to evaluate patterns of mortality among groups of union members. In response to worker concerns, the Union examined mortality at a metal stamping plant, using a method which linked pension records with the State of Michigan computerized death registry. The observed proportion of malignant neoplasms was nearly twice that expected (95% Confidence Limits 1.36, 2.62). Two- to five-fold excess proportional mortality from cancer of the digestive organs, lung cancer, and leukemia accounted for most of the overall excess. Strong associations were found between lung and digestive organ cancer and employment as maintenance welders or millwrights in the plant (odds ratios greater than 10). High levels of six polycyclic aromatic hydrocarbons with mutagenic and carcinogenic properties were found during hot coal tar application to wood block floors, work conducted by the high-risk groups. These levels were substantially reduced following the purchase of new tar pots. The example demonstrates that epidemiologic tools can play a valuable role in occupational health decision making, but care must be taken to avoid mechanical reliance on quantitative testing and to acknowledge the important role of social and political value judgments in the establishment of responsible public policy.

摘要

美国汽车工人国际工会建立了一个流行病学分诊系统,以评估工会成员群体中的死亡率模式。为回应工人关切,该工会利用一种将养老金记录与密歇根州计算机化死亡登记处相联系的方法,对一家金属冲压厂的死亡率进行了调查。观察到的恶性肿瘤比例几乎是预期比例的两倍(95%置信区间为1.36至2.62)。消化系统癌症、肺癌和白血病导致的比例死亡率高出两到五倍,这构成了总体超额死亡率的大部分。在该厂担任维修焊工或机械师的工人中,肺癌和消化系统癌症与工作之间存在强烈关联(优势比大于10)。在高危群体进行的将热煤焦油涂覆在木块地板上的工作过程中,发现了六种具有致突变和致癌特性的多环芳烃含量很高。购买新的焦油罐后,这些含量大幅降低。该例子表明,流行病学工具在职业健康决策中可以发挥重要作用,但必须注意避免机械地依赖定量检测,并认识到社会和政治价值判断在制定负责任的公共政策中的重要作用。